Competition between drug testing and drug taking in bicycle racing

 Some time ago the Cycling Independent Reform Commission (CIRC) issued a report on performance enhancing drugs in bicycle racing, which makes clear that there is vigorous competition between drug taking and drug testing...

CIRC report: 20-90 percent of modern peloton still doping
Doping has waned in professional cycling, but remains a serious issue, the CIRC report contends 

"The days of 15 percent gains in performance through massive EPO doping seem to be a thing of the past, according to CIRC. Instead, riders are skirting the edges of the anti-doping system, taking advantage of Therapeutic Use Exemptions, using overnight gaps in testing and a deep understanding of the Biological Passport to micro-dose without getting caught. Some are taking drugs that aren’t yet banned, like Tramadol, and using pill regimens that dull pain or improve recovery. 

...

"The Athlete’s Biological Passport (ABP), enacted in 2008, is named as a primary catalyst of the change, and a “paradigm shift.”

"CIRC wrote: “Prior to the ABP, only three riders were convicted of blood doping. In the first three years of the ABP, 26 riders were found positive for the presence of EPO stimulating agents in their specimens. In 20 out of the 26 positive cases, it was the abnormal blood profile which raised suspicions leading to a targeted anti-doping urinary or blood test.”

"An unheralded but important landmark in the decrease in doping, according to CIRC, was the introduction in 2008 of anti-doping chaperones at all UCI races. The report cites this change as a catalyst to a cleaner peloton, as riders could no longer quickly prepare for a test with masking agents or similar dodges.

...

"The CIRC concluded that it is still possible to micro-dose using EPO without getting caught by the Biological Passport, largely thanks to the lack of nighttime testing.

"The lack of testing between 11 p.m. and 6 a.m. is a problem, according to the report. Testers are currently barred from testing riders between these hours, unless a rider is under suspicion. This allows for micro-dosing, as “riders are confident that they can take a micro-dose of EPO in the evening because it will not show up by the time the doping control officers could arrive to test at 6 a.m.”

...

"CIRC wrote: “Corticoids are widely used today both to reduce pain and therefore improve endurance capability and to achieve weight loss to improve power/weight ratio.”

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CIRC Report: Executive summary

"The general view is that at the elite level the situation has improved, but that doping is still taking place. It was commented that doping is either less prevalent today or the nature of doping practices has changed such that the performance gains are smaller. The CIRC considers that a culture of doping in cycling continues to exist, albeit attitudes have started to change. The biggest concern today is that following the introduction of the athlete biological passport, dopers have moved on to micro-dosing in a controlled manner that keeps their blood parameters constant and enables them to avoid detection. In contrast to the findings in previous investigations, which identified systematic doping organised by teams, at the elite level riders who dope now organise their own doping programmes with the help of third parties who are primarily outside the cycling team. At the elite level, doping programmes are generally sophisticated and therefore doctors play a key role in devising programmes that provide performance enhancement whilst minimising the risk of getting caught." 

Oregon ends decriminalization of drugs, continues to experiment

 Here's the story in the Washington Post

Hard drugs illegal again in Oregon as first-in-nation experiment ends

"Sunday marks the end of an experiment that drug-reform advocates called a pioneering and progressive measure to better help people. Oregon legislators reassessed Measure 110 this year and decided to again make it a misdemeanor to possess a minor amount of drugs — essentially anything besides marijuana. Selling and manufacturing illicit drugs was and is still illegal in Oregon.

...

"On Feb. 29, the Oregon House of Representatives voted 51-7 to recriminalize drugs, with bipartisan support. The Oregon Senate did the same by a vote of 21-8 the next day. Gov. Tina Kotek (D) signed recriminalization into law April 1.

"Data shows how the [decriminalization] law was used in practice. The Oregonian reported that circuit court data collected by the Oregon Judicial Department from when the law went into effect Feb. 1, 2021, to Aug. 26, 2024, showed that the state’s circuit courts imposed just under $900,000 in fines under the measure but collected only $78,000 of those fines.

"The conviction rate for the 7,227 people cited was 89 percent, with most of those because people didn’t show up to court, the Oregonian reported. Data showed that 85 people completed the substance abuse screening in lieu of a conviction.

"The most commonly cited drug was methamphetamine, accounting for 54 percent of citations. Fentanyl and other Schedule II drugs, the Oregonian reported, ranked second at 31 percent."

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And here's the Guardian's coverage:

Oregon: drug possession to be a crime again as decriminalization law expires. First-in-nation trial comes to an end, as new law gives those caught with hard drugs option of charges or treatment

"The new recriminalization law, HB4002, will give those caught with illicit drugs – including fentanyl, heroin and meth – the choice to either be charged with possession or treatment, which includes completing a behavioral health program and participating in a “deflection program” to avoid fines.

"Personal-use possession would be a misdemeanor punishable by up to six months in jail. It aims to make it easier for police to crack down on drug use in public and introduced harsher penalties for selling drugs near places such as parks.

"The recriminalization law encourages, but does not mandate, counties to create treatment alternatives to divert people from the criminal justice system and toward addiction and mental health services."

Optimism and pessimism on psychedelic drugs as medicine

 "Psychedelics" may prove to be a broad church, with psilocybin and LSD quite different from MDMA, etc., but here are two articles that express very different views about the progress towards making them part of standard medical practice.

Here's some optimism in Columbia Magazine:

The Magic and Mystery of Psychedelic Therapies.  As new trials show that psilocybin and LSD may help treat depression and anxiety, mental-health providers get ready for a revolution.  By Paul Hond |

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And here's some pessimism, in the NYT:

How Psychedelic Research Got High on Its Own Supply, By Caty Enders

"The drug company Lykos Therapeutics had spent much of this year expecting to vault to meteoric heights. It had sent an application to the Food and Drug Administration seeking approval to use MDMA to treat post-traumatic stress disorder. Lykos expected F.D.A. approval; it was banking on it.

"And then on Aug. 9, the F.D.A.’s decision came through: rejection. It was the capstone to months of increasingly loud concerns being voiced over the quality of Lykos’s clinical trials. And in the wake of the F.D.A. decision, the journal Psychopharmacology retracted three papers related to research on MDMA, citing “unethical conduct,” an apparent reference to allegations of sexual abuse on the part of an unlicensed therapist at one of the trial sites. Several of the authors of the retracted papers were affiliated with Lykos.

"It is a shocking decrescendo for a drug that had been promoted for years as best positioned to lead a psychedelic mental health revolution. The F.D.A.’s rejection signals greater uncertainty for the future of psychedelic medicine."

Are Swedish gangs becoming the hitmen of Scandanavia?

 We're accustomed to drug violence among gangs even in wealthy countries, but here's a story from The Times (of London) suggesting that the drug and biker gangs in Sweden are going in for contract killing as well.

How Swedish gangs are exporting young contract killers across Scandinavia. Crime bosses are behind a wave of youths being hired for attacks in Denmark and Norway, with fears the trend could spread further

"Sweden is accused of exporting its gang violence problem to its Nordic neighbours after at least 25 young Swedes on suspected contract-killing or bombing missions were arrested in Denmark over the past four months.

...

"Part of the problem, according to Markus Kaakinen, a criminologist at the University of Helsinki, is that Sweden’s notoriously trigger-happy drug gangs are outgrowing their home market. As a result they are not only setting up distribution outposts in countries such as Norway and Finland but are also moving in on “transit” states that serve as conduits for the international drug trade, such as Denmark and Spain, where they compete with the local criminal networks.

...

"Yet that is not the main thing that bothers experts. What really worries them is a previously unknown phenomenon: Swedish youths are being anonymously hired through social media for acts of violence in Denmark, as though they were Deliveroo drivers.

“This is something very new: the recruiting of very young, completely unknown adolescents,” Kaakinen said. “There’s increasing demand for violence and these gangs have noticed that it’s less risky for them to use these channels.”

...

"he Swedish authorities are already having a hard enough time getting a grip on their country’s conventional gang wars, where kingpins with nicknames such as the “Kurdish Fox”, “The Strawberry” and “The Greek” pursue their vendettas through teenage amateur assassins hired on a semi-freelance basis.

...

"Danish ministers feel their state has dealt relatively well with its own problems along similar lines. There are estimated to be about 1,500 active gang members in a population of 5.9 million, while Sweden has roughly 14,000 in a population of 10.5 million."

Black markets in everything bagels (in S. Korea)

 South Korea is not a hub of everything bagels, it turns out. In fact they are banned.

The NYT has the story:

Why Everything Bagel Seasoning Was Banned in South Korea. The seasoning is sold by Trader Joe’s, a brand whose popularity has skyrocketed in the region in recent years.By Eve Sampson

"Food containing poppy seeds, “including popular bagel seasoning blends,” is considered contraband in South Korea, according to the U.S. Embassy, making the coveted topping a forbidden treat.

...

"As more travelers have tried to bring the popular seasoning mix into South Korea, local news and social media sites have reported in recent weeks on an increase in confiscations at airports.

"Poppy seeds are not opiates but may be contaminated by the plant’s fluid, which contains opiates, when they are harvested. 

...

"In South Korea, poppy seeds are banned because they are considered a narcotic.

...

"South Korea is among the few countries with laws regulating poppy seeds. The United Arab Emirates bans the seed, and Singapore requires anyone wishing to import poppy seeds to submit a sample for opiate testing.

"In the United States, there has also been mixed messaging about poppy seeds. In 2023, the Department of Defense warned members of the military that eating poppy seeds could result in a positive drug test, despite the military previously feeding service members poppy seed breads in ready-to-eat meals."

Nicotine is hard to ban: Juul wins a reprieve from the FDA, and illegal vapes flood the market

 Here are two stories by Jennifer Maloney at the WSJ:

FDA Rescinds Juul Ban, Opening Door for Federal Clearance. E-cigarette maker’s products have stayed on market pending appeal of 2022 ban.. By  Jennifer Maloney

"The Food and Drug Administration rescinded its 2022 ban on Juul Labs’s e-cigarettes. The agency hasn’t yet reached a final determination on whether they can stay on the U.S. market, but the move opened the possibility for federal clearance.

The FDA in 2022 ordered Juul to halt its sales, then stayed the order pending the vaping company’s appeal. The agency said Thursday that it was placing Juul’s products back under scientific review, essentially moving them back to their regulatory status before the ban. 

...

"Juul’s products remain on the market. The FDA didn’t give a timeline for a final decision on whether they can stay there. Juul is the No. 2 e-cigarette maker in the U.S.

Juul and other e-cigarette manufacturers in 2020 were required to submit scientific research to demonstrate that their vaping products exposed users to fewer carcinogens than cigarettes and that the benefit of helping adult smokers switch to a safer alternative outweighed the potential harm of hooking young people on nicotine.

...

"The FDA ban, though it was quickly put on hold, sent Juul into a financial tailspin. The company narrowly averted bankruptcy. Juul has since submitted next-generation vaping products for FDA review. They aren’t yet for sale in the U.S."

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U.S. Pledges Crackdown on Illegal E-Cigarettes. FDA and DOJ form task force to go after fruity, disposable vapes flooding the market.  By Jennifer Maloney

"Big tobacco companies and their critics agree on at least one thing: The illegal, fruit-flavored, disposable vapes that are popular among teenagers have flooded the U.S. market and federal regulators haven’t done enough to stop it.

"The Food and Drug Administration and Justice Department said Monday they are stepping up enforcement by forming a multiagency task force to go after the illegal distribution and sale of e-cigarettes.

"Disposable vaping devices, almost none of which are authorized for sale by the FDA, represent more than 30% of U.S. e-cigarette sales in stores tracked by Nielsen, according to an analysis by Goldman Sachs. Many of them are imported from China. Breeze Pro and Elfbar, both of which were ordered off the market last year by the FDA, remain the top two disposable e-cigarette brands in the U.S.

"Njoy is the only disposable vaping brand authorized for sale by the FDA." 

Marijuana policy and use in the U.S., 1979-2022, by Jonathan Caulkins, in Addiction

 Here's a paper forthcoming in the journal Addiction:

Changes in self-reported cannabis use in the United States from 1979 to 2022, by Jonathan P. Caulkins, published online 22 May 2024, https://doi.org/10.1111/add.16519 

"Abstract

Background and aims: Multiple countries are considering revising cannabis policies. This study aimed to measure long-term trends in cannabis use in the United States and compare them with alcohol use.

Design and setting: Secondary analysis of United States general population survey data.

Participants: The national surveys had a total of 1 641 041 participants across 27 surveys from 1979 to 2022.

Measurements: Rates of use reported to the US National Survey on Drug Use and Health and its predecessors are described, as are trends in days of use reported. Four milepost years are contrasted: 1979 (first available data and end of relatively liberal policies of the 1970s), 1992 (end of 12 years of conservative Reagan-Bush era policies), 2008 (last year before the Justice Department signaled explicit federal non-interference with state-level legalizations) and 2022 (most recent data available).

Findings: Reported cannabis use declined to a nadir in 1992, with partial recovery through 2008, and substantial increases since then, particularly for measures of more intensive use. Between 2008 and 2022, the per capita rate of reporting past-year use increased by 120%, and days of use reported per capita increased by 218% (in absolute terms from the annual equivalent of 2.3 to 8.1 billion days per year). From 1992 to 2022, there was a 15-fold increase in the per capita rate of reporting daily or near daily use. Whereas the 1992 survey recorded 10 times as many daily or near daily alcohol as cannabis users (8.9 vs. 0.9 M), the 2022 survey, for the first time, recorded more daily and near daily users of cannabis than alcohol (17.7 vs. 14.7 M). Far more people drink, but high-frequency drinking is less common. In 2022, the median drinker reported drinking on 4–5 days in the past month, versus 15–16 days in the past month for cannabis. In 2022, past-month cannabis consumers were almost four times as likely to report daily or near daily use (42.3% vs. 10.9%) and 7.4 times more likely to report daily use (28.2% vs. 3.8%).

Conclusions: Long-term trends in cannabis use in the United States parallel corresponding changes in cannabis policy, with declines during periods of greater restriction and growth during periods of policy liberalization. A growing share of cannabis consumers report daily or near daily use, and their numbers now exceed the number of daily and near daily drinkers."

Daily and Near Daily (DND) use

...

"That is still not as high as for cigarettes. The 2022 NSDUH survey finds that 58.7% of PM ["Past Month"] cigarette smokers smoked ‘daily’—defined as ‘smoked one or more packs of cigarettes per day’ [8]. Therefore, there are more daily cigarette smokers than DND PM marijuana users (24.1 vs 17.7 million). 3 Still, patterns of marijuana consumption have shifted from being like alcohol to being closer to cigarette use. It is also no longer a young person's drug. In 2022, people 35 and older accounted for (slightly) more days of use than did those under the age of 35."

Still illegal in Idaho

 Here's a map from The Hill of places where marijuana will be legal to various degrees by the end of this year. Grey states are where marijuana is still entirely illegal.  Despite the best attempts of the previous presidential administration to make America grey again, Idaho is one of only three states that remain grey: they are surrounded by states in which cannabis is legal in some form, and most of Idaho's neighbors have legalized marijuana (even) for recreational purposes (bright green on the map).

But Idaho is holding the line, which seems to be politically popular there.

The NYT has the story:

A Legal Pot Pioneer Was Busted in Idaho With 56 Pounds. He Has a Plan.  By Corey Kilgannon

"In retrospect, the Idaho shortcut might have been a bad idea.

...

"Idaho is surrounded mostly by pot friendly states and is strict about people driving through with the stuff. The authorities are especially vigilant in “corridor counties” along Interstate 84, of which Gooding County — where Mr. Beal encountered the state police — is one.

"Under state law, carrying more than 25 pounds of marijuana is a felony with a mandatory minimum sentence of five years; the maximum is 15 years, with a maximum fine of $50,000.

“It’s one of the worst places in the country to possess marijuana, definitely,” Michelle Agee, Mr. Beal’s court-appointed lawyer, said. “Idaho is stuck in the 1950s as far as marijuana goes. It’s definitely the wrong place, wrong time for a person to be accused of having marijuana.”

...

"Reached for comment, Idaho’s attorney general, Raúl R. Labrador, a former Republican congressman who helped found the conservative House Freedom Caucus, said that legalization in neighboring states had done nothing to deter the strict enforcement of the laws in Idaho.

“We’ve watched how those decisions to legalize drugs have ruined other states, and Idaho demands just a bit better for our citizens and communities,” he said. “If you are trying to transport marijuana across state lines through Idaho, take the long way instead. It’ll save us money on your incarceration.”

Cannabis in US airports

 An anomaly of US Federal law is that marijuana is illegal on airplanes (interstate commerce) even when the airports involved are in states where marijuana is legal.

The WSJ has the story and a picture:

Don’t Put Your Stash in the Overhead Bin. A ‘Cannabis Amnesty Box’ at Chicago’s Midway Airport.  By Bob Greene

Oregon is re-criminalizing drugs

 The war on drugs is unforgiving, and neither criminalization nor decriminalization seems to be a winning strategy.  The NYT has the latest from Oregon, where there were high hopes for decriminalization and harm reduction, and where there are now second thoughts. 

Oregon Is Recriminalizing Drugs, Dealing Setback to Reform Movement. Oregon removed criminal penalties for possessing street drugs in 2020. But amid soaring overdose deaths, state lawmakers have voted to bring back some restrictions.  By Mike Baker

"Three years ago, when Oregon voters approved a pioneering plan to decriminalize hard drugs, advocates looking to halt the jailing of drug users believed they were on the edge of a revolution that would soon sweep across the country.

"But even as the state’s landmark law took effect in 2021, the scourge of fentanyl was taking hold. Overdoses soared as the state stumbled in its efforts to fund enhanced treatment programs. And while many other downtowns emerged from the dark days of the pandemic, Portland continued to struggle, with scenes of drugs and despair.

"Lately, even some of the liberal politicians who had embraced a new approach to drugs have supported an end to the experiment. On Friday, a bill that will reimpose criminal penalties for possession of some drugs won final passage in the State Legislature and was headed next to Gov. Tina Kotek, who has expressed alarm about open drug use and helped broker a plan to ban such activity.

“It’s clear that we must do something to try and adjust what’s going on out in our communities,” State Senator Chris Gorsek, a Democrat who had supported decriminalization, said in an interview. Soon after, senators took the floor, with some sharing stories of how addictions and overdoses had impacted their own loved ones. They passed the measure by a 21-8 margin."

Prison gangs, in Latin America and in the U.S.

 It's one thing to be able to capture and confine prisoners. When gangs are involved, it's quite another thing to control the prisons, or the ability of prisoners to continue to control gang activity outside of prison.

The NYT has the story, from Latin America:

In Latin America, Guards Don’t Control Prisons, Gangs Do. Intended to fight crime, Latin American prisons have instead become safe havens and recruitment centers for gangs, fueling a surge in violence. By Maria Abi-Habib, Annie Correal and Jack Nicas

"Inside prisons across Latin America, criminal groups exercise unchallenged authority over prisoners, extracting money from them to buy protection or basic necessities, like food.

"The prisons also act as a safe haven of sorts for incarcerated criminal leaders to remotely run their criminal enterprises on the outside, ordering killings, orchestrating the smuggling of drugs to the United States and Europe and directing kidnappings and extortion of local businesses.

"When officials attempt to curtail the power criminal groups exercise from behind bars, their leaders often deploy members on the outside to push back.

“The principal center of gravity, the nexus of control of organized crime, lies within the prison compounds,” said Mario Pazmiño, a retired colonel and former director of intelligence for Ecuador’s Army, and an analyst on security matters.

“That’s where let’s say the management positions are, the command positions,” he added. “It is where they give the orders and dispensations for gangs to terrorize the country.”

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I wrote a related post in November (see below) about a Brazilian prison gang, and received an illuminating email from Professor David Skarbek of Brown University, saying

"I enjoyed your blog post about the PPC Brazilian prison gang. I thought that you might be interested to know that the same phenomenon exists in the US as well. I'm attaching a piece I published in the American Political Science Review on the Mexican Mafia in Southern California."

Here's the link to that article:

Skarbek, David. "Governance and prison gangs." American Political Science Review 105, no. 4 (2011): 702-716.

Abstract: How can people who lack access to effective government institutions establish property rights and facilitate exchange? The illegal narcotics trade in Los Angeles has flourished despite its inability to rely on state-based formal institutions of governance. An alternative system of governance has emerged from an unexpected source—behind bars. The Mexican Mafia prison gang can extort drug dealers on the street because they wield substantial control over inmates in the county jail system and because drug dealers anticipate future incarceration. The gang's ability to extract resources creates incentives for them to provide governance institutions that mitigate market failures among Hispanic drug-dealing street gangs, including enforcing deals, protecting property rights, and adjudicating disputes. Evidence collected from federal indictments and other legal documents related to the Mexican Mafia prison gang and numerous street gangs supports this claim.

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Earlier

Tuesday, November 21, 2023

Balance of violence: prison-based criminal cartels, the case of Brazil's PCC.

Guns and drugs on the U.S. Mexico border

 Here are two stories about some of the illegal traffic on the border between the U.S. and Mexico.

First, the war on drugs is fought with American guns on both sides:

The NY Times has the story:

Appeals Court Revives Mexico’s Lawsuit Against Gunmakers. The decision, which is likely to be appealed, is one of the most significant setbacks for the gun industry since passage of a federal law that provided immunity from some lawsuits.  By Glenn Thrush  Jan. 22, 2024

"A federal appeals panel in Boston ruled on Monday that a $10 billion lawsuit filed by Mexico against U.S. gun manufacturers whose weapons are used by drug cartels can proceed, reversing a lower court that had dismissed the case.

"The decision, which is likely to be appealed, is one of the most significant setbacks for gunmakers since passage of a federal law nearly two decades ago that has provided immunity from lawsuits brought by the families of people killed and injured by their weapons.

"Mexico, in an attempt to challenge the reach of that law, sued six manufacturers in 2021, including Smith & Wesson, Glock and Ruger. It contended that the companies should be held liable for the trafficking of a half-million guns across the border a year, some of which were used in murders.

...

" lawyers for Mexico, assisted by U.S. gun control groups, claimed that the companies “aided and abetted the knowingly unlawful downstream trafficking” of their guns into Mexico.

"Gun violence is rampant in Mexico despite its near-blanket prohibition of firearms ownership.

"About 70 to 90 percent of guns trafficked in Mexico originated in the United States, according to Everytown Law, the legal arm of the gun control group founded by the former mayor of New York Michael R. Bloomberg.

"Gun control advocates hailed the decision on Monday by a three-judge panel, describing it as a milestone in holding the gun industry accountable."

***********

As for drugs, it turns out that harm reduction drugs are highly controlled in Mexico, so illegal drugs also flow both ways.

Here's that story, from the Guardian:

Carriers sneak life-saving drugs over border as Mexico battles opioid deaths  People forced to bring overdose-reversal drug naloxone from US, as critics accuse Mexican government of creating shortage. by Thomas Graham in Tijuana, Tue 23 Jan 2024 

"Every day, people cross the US-Mexico border with drugs – but not all of them are going north. Some head in the opposite direction with a hidden cargo of naloxone, a life-saving medicine that can reverse an opioid overdose but is so restricted as to be practically inaccessible in Mexico.

"This humanitarian contraband is necessary because Mexico’s border cities have their own problems with opioid use – problems that activists and researchers say are being made more deadly by government policy.

“Mexico has long seen itself as a production and transit country, but not a place of consumption,” said Cecilia Farfán Méndez, a researcher at the University of California at San Diego. “And a lot of the conversation is still around that being a US problem – not a Mexican one.”

...

"The situation has been exacerbated by a government policy that, aside from cutting budgets for harm reduction services like PrevenCasa, has also created shortages of life-saving medicines for opioid users.

"In response to the fentanyl crisis, authorities in the US made naloxone available without a prescription. Naloxone vending machines have proliferated across the country.

"But in Mexico naloxone remains strictly controlled – despite the efforts of some senators from Andrés Manuel López Obrador’s own party, Morena, who proposed a law to declassify it.

"The president, popularly known as Amlo, has criticised naloxone, asking whether it did any more than “prolong the agony” of addicts, and questioning who stood to profit from its sale."

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Earlier:

Sunday, January 22, 2023

The trade in guns and drugs on the Mexico-US border

The war on drugs is a war

The war on drugs doesn't begin at U.S. borders.

Here's a dispatch from Ecuador, in the WSJ:

Ecuador Is at War With Drug Gangs, President Says. Troops patrolled the country’s largest city a day after a series of attacks against the new government  By Kejal Vyas and Ryan Dubé

"Ecuador is at war with drug gangs, President Daniel Noboa said Wednesday, as troops patrolled the country’s largest city, Guayaquil, a day after gunmen took over a TV studio and launched a series of attacks against the Andean nation’s new government.

“We are in a noninternational armed conflict,” Noboa said in a radio interview. “We are in a state of war. We cannot give in to those terrorist groups.”

"The armed forces and national police scrambled to bring order to Guayaquil, and shops and schools were closed after a series of coordinated attacks Tuesday on shopping centers, hospitals and a university left at least 11 people dead.

"Drug-trafficking gangs in recent years have turned Ecuador into one of the world’s most violence-plagued nations as they battled over the cocaine trade.

...

" Once relatively peaceful, Ecuador has seen the homicide rate shoot up from less than six per 100,000 in 2018 to more than 40 in 2023, said police."

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And here's one from Belgium, in the Washington Post:

A Belgian port seized tons of cocaine. Criminals tried to take it back.

Belgian customs officers seized three times as much cocaine in the port of Antwerp last year as U.S. customs and border officials seized in all of the United States.  By Gerrit De Vynck

"The head of Belgium’s customs service said in an interview that especially big seizures in the fall appeared to have prompted a violent backlash, along with a new issue: Authorities haven’t always been able to destroy what they’ve confiscated before drug gangs try to steal it back.

“Attacking the police, attacking the customs, this is not something you see in Europe,” said Kristian Vanderwaeren, director general of Belgium’s customs agency. “I was really afraid that my people would be killed if this would continue.”

...

"“The criminal organization was not afraid to come to a facility and capture their cocaine, even if it meant they would kill a customs officer,” Vanderwaeren said.

...

"According to Europol, the European Union’s law enforcement agency, Ecuador and its main port of Guayaquil have been the biggest sources of cocaine destined for Europe, reflecting how Mexican and Albanian gangs have infiltrated the country. This month, the president of Ecuador declared a “state of war” against drug gangs, after a series of assassinations, prison breaks and bombings there."

Some year-end good news: U.S. homicides are down

To put deaths in their grim perspective, we have a lot more deaths from drug overdoses than from homicides.  But we're headed in the right direction on one of those. 

The NYT has the story:

After Rise in Murders During the Pandemic, a Sharp Decline in 2023. The country is on track for a record drop in homicides, and many other categories of crime are also in decline, according to the F.B.I. By Tim Arango and Campbell Robertson  Dec. 29, 2023

"In 2020, as the pandemic took hold and protests convulsed the nation after the murder of George Floyd by a police officer in Minneapolis, the United States saw the largest increase in murders ever recorded. Now, as 2023 comes to a close, the country is likely to see one of the largest — if not the largest — yearly declines in homicides, according to recent F.B.I. data and statistics collected by independent criminologists and researchers.

"The rapid decline in homicides isn’t the only story. Among nine violent and property crime categories tracked by the F.B.I., the only figure that is up over the first three quarters of this year is motor vehicle theft. The data, which covers about 80 percent of the U.S. population, is the first quarterly report in three years from the F.B.I., which typically takes many months to release crime data.

Limitations of harm reduction: will Oregon recriminalize drug use?

 The NYT has the story:

To Revive Portland, Officials Seek to Recriminalize Public Drug Use. State and local leaders are proposing to roll back part of the nation’s pioneering drug decriminalization law and step up police enforcement.  by Mike Baker

"After years of rising overdoses and an exodus of business from central Portland, Oregon Gov. Tina Kotek said on Monday that state and city officials are proposing to roll back a portion of the nation’s most wide-ranging drug decriminalization law in a bid to revive the troubled city.

"Under the plan brokered by Gov. Kotek, a Democrat, state lawmakers would be asked to consider a ban on public drug use and police would be given greater resources to deter the distribution of drugs. Ms. Kotek said officials hoped to restore a sense of safety for both visitors and workers in the city’s beleaguered urban core, which has seen an exodus of key retail outlets, including REI, an institution in the Pacific Northwest.

“When it comes to open-air drug use, nobody wants to see that,” Ms. Kotek said in an interview. “We need different tools to send the message that that is not acceptable behavior.”

...

"Oregon voters in 2020 approved the nation’s first law decriminalizing possession of small amounts of hard drugs, including fentanyl, heroin and methamphetamines. The ballot measure sought to end the use of jail as a punishment for drug users and instead treat addiction as a health issue. The effort was to be joined with major new investments in drug treatment, but those new systems have been slow to develop.

...

"Last month, Seattle implemented a new law that prohibits possession of drugs and public use.

...

"Ms. Kotek’s task force does not have the power to immediately ban public drug use, but the panel called for the Legislature to take up the issue in the coming session along with changes that could reduce barriers to prosecuting those who deliver drugs. Lawmakers have already been discussing potential changes to the decriminalization law."

Drug addiction: not just opioids

 Consumption of addictive drugs seems to come in deadly cocktails these days, which is making interdiction of drugs, and treatment of addiction more complicated.

The NYT has the story:

‘A Monster’: Super Meth and Other Drugs Push Crisis Beyond Opioids. Millions of U.S. drug users now are addicted to several substances, not just opioids like fentanyl and heroin. The shift is making treatment far more difficult.  By Jan Hoffman

"The United States is in a new and perilous period in its battle against illicit drugs. The scourge is not only opioids, such as fentanyl, but a rapidly growing practice that the Centers for Disease Control and Prevention labels “polysubstance use.”

Over the last three years, studies of people addicted to opioids (a population estimated to be in the millions) have consistently shown that between 70 and 80 percent also take other illicit substances, a shift that is stymieing treatment efforts and confounding state, local and federal policies.

“It’s no longer an opioid epidemic,” said Dr. Cara Poland, an associate professor at the Michigan State University College of Human Medicine. “This is an addiction crisis.”

...

"The incursion of meth has been particularly problematic. Not only is there no approved medical treatment for meth addiction, but meth can also undercut the effectiveness of opioid addiction therapies. Meth explodes the pleasure receptors, but also induces paranoia and hallucinations, works like a slow acid on teeth and heart valves and can inflict long-lasting brain changes.

"The Biden administration has been pouring billions into opioid interventions and policing traffickers, but has otherwise lagged in keeping pace with the evolution of drug use. There has been comparatively little discussion about meth and cocaine, despite the fact that during the 12-month period ending in May 2023, over 34,000 deaths were attributed to methamphetamine and 28,000 to cocaine, according to provisional federal data.

...

"Like opioids, which originally came from the poppy, meth started out as a plant-based product, derived from the herb ephedra. Now, both drugs can be produced in bulk synthetically and cheaply. They each pack a potentially lethal, addictive wallop far stronger than their precursors."

Balance of violence: prison-based criminal cartels, the case of Brazil's PCC.

The vexed relationship between banned markets and black markets is perhaps nowhere clearer than when prison based gangs of convicted drug dealers are able to extend their empires outside of prisons. While national authorities are able to capture, convict and imprison gang leaders, those gangs retain the ability to organize violence not only inside prisons but outside of them, and hence operate national and international black markets as well.

The Guardian has the story:

How a Brazilian prison gang became an international criminal leviathan  by Tom Phillips

"The PCC – First Capital Command – arose in the country’s notoriously brutal penitentiaries 30 years ago but now controls a billion-dollar drug trade supplying much of Europe’s cocaine,

...

"For much of its 30-year existence the PCC has been considered a jailhouse fraternity, which recruited incarcerated “brothers” such as the Venezuelan by offering them protection within Brazil’s violent, overcrowded prisons. Created in August 1993, it grew into Brazil’s most feared criminal faction, conquering drug markets, smuggling routes, shantytowns and prisons across Brazil, including in far-flung corners of the Amazon. It also became a major player in other South American countries such as neighbouring Paraguay where the group has been blamed for multimillion-dollar armed robberies and bombings and targeted assassinations.

But over the past five years, investigators say the PCC – which the US now calls one of the world’s most powerful organized crime groups – has morphed into an even more formidable force after forging lucrative alliances with partners ranging from Bolivian cocaine producers to Italian mafiosi. Today, the group boasts tens of thousands of members and has a growing portfolio of interests, including illegal goldmines in the Amazon. It controls one of South America’s most important trafficking routes – linking Bolivia and Brazil to Europe and Africa – and is partly responsible for a tsunami of cocaine that has brought car bombings, assassinations and gunfights to parts of Europe.

...

"During the 1990s, the PCC tightened its grip on São Paulo’s prison system but largely flew under the radar until thousands of guards and visitors were captured during a massive 2001 uprising. Five years later the group again made headlines, bringing São Paulo to a virtual standstill with a wave of coordinated attacks on police that caused hundreds of deaths.

...

"Having dominated much of Brazil’s domestic drug market – and established a monopoly over São Paulo’s crime scene – Gakiya said the PCC began looking overseas in late 2016. Deals were struck with Italy’s most powerful mafia group, the ’Ndrangheta, as well as Serbian and Albanian mafias, and the PCC began shipping tonnes of cocaine from Brazilian ports to Europe.

...

"Marcola, 55, who is serving a 342-year prison sentence for murder, robbery and drug trafficking, is also not a man to be crossed. In late 2018, Gakiya decided to transfer him to a high-security federal prison after the discovery of an audacious multimillion-dollar plot to free him with the help of foreign mercenaries, helicopters and anti-aircraft guns. “I knew it might change my life but I also realized it needed doing,” the prosecutor said, admitting he did not consult his family first.

Gakiya was no stranger to death threats, but moving Marcola turned his life upside down. PCC leaders issued a “decree” calling for the prosecutor’s assassination, condemning Gakiya to a reclusive existence he compared to the life of Giovanni Falcone, the anti-mafia crusader assassinated in 1992. “I hope, of course, not to share the same fate as Falcone,” added Gakiya..."

The broken market for antibiotics, continued

 Not only is the market for new antibiotics broken, companies that explore them are going broke.

Here's a story from the WSJ:

The World Needs New Antibiotics. The Problem Is, No One Can Make Them Profitably.  New drugs to defeat ‘superbug’ bacteria aren’t reaching patients   By Dominique Mosbergen

"The push for antibiotics to fight fast-evolving superbugs is snagging on a broken business model. 

"Six startups have won Food and Drug Administration approval for new antibiotics since 2017. All have filed for bankruptcy, been acquired or are shutting down. About 80% of the 300 scientists who worked at the companies have abandoned antibiotic development, according to Kevin Outterson, executive director of CARB-X, a government-funded group promoting research in the field.  

...

"The reason, the companies say: They couldn’t sell their lifesaving products because the system that produces drugs for cancer and Alzheimer’s disease—which counts on companies selling enough of a new treatment or charging a high enough price to reward investors and make a profit—isn’t working for antibiotics. 

New antibiotics are meant to be used rarely and briefly to defeat the most pernicious infections so bacteria don’t develop resistance to them too quickly. Companies have priced them at 100 times as much as the generic antibiotics doctors have prescribed for decades that cost a few dollars per dose. Most have sold poorly. 

...

"Most large pharmaceutical companies aren’t developing antibiotics. Several have closed or divested antibiotic development programs. “There’s no profitability,” Hyun said. "