Monday, June 11, 2018

The market for blood plasma: different tissues, same issues

I'll be speaking at The Plasma Protein Forum, June 12-13 in Washington D.C., on "REPUGNANT TRANSACTIONS AND FORBIDDEN MARKETS: DIFFERENT TISSUES, SAME ISSUES"

Here's the whole program:

DAY ONE:    JUNE 12, 2018

7:00 am–5:30 pmRegistration and Exhibit Hall Open
7:00–8:30 amBreakfast—Available in Exhibit Halls 1 & 2
8:30–8:45 amWELCOME & “How Is Your Day?Jan M. Bult, President & CEO, PPTA
8:45–9:00 amCHAIRMAN'S MESSAGE
David Bell, Chair, PPTA Global Board of Directors; Executive Vice President & General Counsel, Grifols
9:00–10:30 am  PERSPECTIVES: ACCESS TO CARE
Moderator:  Larisa Cervenakova, M.D., Ph.D., Medical Director, PPTA
Speakers: 
  • Tony Castaldo, President, US Hereditary Angioedema AssociationHAE perspective
  • Joanna Chorostowska-Wynimko M.D., Ph.D., D.Sc., Professor, Scientific Director National Institute of Tuberculosis and Lung Diseases, Warsaw, Poland
    Alpha-1 perspective

  • Professor Paolo Caraceni, Associate Professor, Department of Medical and Surgical Sciences, University of Bologna, Bologna, ItalyANSWER: Long term albumin administration improves survival in patients with decompensated cirrhosis
10:3011:00 amBREAK
11:00 am–12:30 pm  CURRENT INDUSTRY AND REGULATORY INITIATIVES IN THE AREAS OF INSPECTIONS AND DONOR HEALTH
Moderator:  John Delacourt, Vice President Legal Affairs & Global Operations, PPTA
Speakers:
  • Ginette Y. Michaud, M.D., Director, Office of Biological Products Operations, U.S. Food & Drug AdministrationFDA’s Office of Biological Products Operations – Form Follows Function
  • Toby L. Simon, M.D., Senior Medical Director, Plasma & Plasma Safety, CSL PlasmaDonor health perspectives: Insights from industry plasma vigilance data and future safety initiatives
  • George B. Schreiber, Sc.D., DirectorEpidemiology, PPTA
    Iron depletion in Source plasma donors; A non sequitur.
12:30–2:00 pm
LUNCHBuffet Available in Exhibit Halls 1 & 2    Sponsored by:  DIAMOND Roche Logo 01
2:00–4:00 pm  INTERNATIONAL ACCESS TO CARE LANDSCAPE
Moderator:  Jan M. Bult, President & CEO, PPTA
Speakers:
  • P. Martin van Hagen, M.D., Ph.D., Professor, Head, Clinical Immunology Unit Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands
    Is personalized medicine a national or cross border issue?
  • Dr. Ranjeet S. Ajmani, CEO, PlasmaGen BioSciences Pvt Ltd.
    Initiatives to improve access to care in India
  • Antonio Condino-Neto, M.D., Ph.D., President, Latin American Society for Immunodeficiencies (LASID)What needs to be done to improve access to Immunoglobulin therapy in Brazil? Diagnosis, Access, Supply
4:00 pm BREAK – Ice cream social
4:30 pmOtto Schwarz Award presentation
5:00 pmREPUGNANT TRANSACTIONS AND FORBIDDEN MARKETS: DIFFERENT TISSUES, SAME ISSUES
  • Alvin E. Roth, Craig and Susan McCaw Professor of Economics, Stanford University; George Gund Professor of Economics and Business Administration, Emeritus, Harvard University; and 2012 recipient of the Nobel Memorial Prize in Economic Sciences
5:45 pmDAY 1 CLOSING ANNOUNCEMENTS
5:45–7:30 pmReception        PPTA How is your day logo v2

DAY TWO:    JUNE 13, 2018

7:30 am–1:00 pmRegistration and Exhibit Hall open
7:30–8:30 amBreakfast—Available in Exhibit Halls 1 & 2
8:30–8:35 amWELCOME
Joshua Penrod, J.D., Ph.D., Vice President, Source & International Affairs, PPTA

8:35–8:50 amSOURCE DIVISION OUTLOOK
Roger Brinser, ‎Chair, PPTA Source Board of Directors; Director, Regulatory, BioLife Plasma Services/Shire

8:50–11:00 am CURRENT CHALLENGES 
Moderator: Joshua Penrod, J.D., Ph.D., Vice President, Source & International Affairs, PPTA
Speakers:
  • Nicola Lacetera, Ph.D., Associate Professor at the University of Toronto
    Crowding Out
  • Prof Dr. Liu ZhongVice President, Institute of Blood Transfusion, Chinese Academy of Medical Sciences (CAMS)Which is safer source plasma for manufacturing in China: apheresis plasma or recovered plasma?
  • Chen BinDeputy Director, Medical Safety and Transfusion Division, Department of Medical Regulatory and Management, National Health CommissionThe current situation and challenge of the Chinese plasma management

11:00–11:30 amBREAK
11:30 am–1:00 pm CAN COUNTRIES DELIVER ON THEIR OWN?
Moderator:  Julia Fabens, Senior Manager International Affairs, PPTA

Speakers:
  • Bill Bees, Vice President, Plasma Technologies, Prometic Plasma ResourcesCanada–Debunking the Krever Commission Report
  • Peter Jaworski, Ph.D., Professor, Georgetown University, Washington, D.C.
    Ethics of Compensation
  • Joshua Penrod, J.D., Ph.D., Vice President, Source & International Affairs, PPTAGlobal sufficiency: Obstacles and opportunities

***********
Here are my blog posts on plasma, sorted by date (most recent first), going back to one from 2009.

Sunday, June 10, 2018

Computing fairness

One of the areas in which computer science and economics touch each other more than a bit is in understanding what constitutes a fair way of allocating scarce resources.  This was the subject of a recent Northwestern CS workshop:

Quarterly Theory Workshop: Algorithmic Fairness

"Synopsis: As algorithmic systems have increasingly been deployed to make consequential decisions, it is becoming urgent that we grapple with the problem of (un)fairness and discrimination. These are delicate issues — to think rigorously about them, we first need to figure out how to formally define what we want, and then reason about how we might go about achieving our goals algorithmically — and what tradeoffs we will have to manage. This workshop focuses on recent advances in the theory of algorithmic fairness: both on foundational definitional questions, and on algorithmic techniques. The speakers are Nicole Immorlica (MSR), Jon Kleinberg (Cornell), Omer Reingold (Stanford), and Aaron Roth (U. of Pennsylvania).
The technical program of this workshop is organized by Aaron Roth and Jason Hartline."

These were the talks:
Speaker: Jon Kleinberg
Title: Algorithmic Fairness Criteria for Evaluating Individuals and Sets
Abstract: Recent discussion in the public sphere about classification by algorithms has involved tension between competing notions of what it means for such a classification to be fair to different groups. We consider several of the key fairness conditions that lie at the heart of these debates, and discuss recent research establishing inherent trade-offs between these conditions. We also consider a variety of methods for promoting fairness and related notions for classification and selection problems that involve sets rather than just individuals.
This talk is based on joint work with Sendhil Mullainathan, Manish Raghavan, and Maithra Raghu.
Speaker: Aaron Roth
Title: Preventing Fairness Gerrymandering in Machine Learning
Abstract: The most prevalent notions of fairness in machine learning are statistical notions: they fix a small collection of high-level, pre-defined groups (such as race or gender), and then ask for approximate parity of some statistic of the classifier (like positive classification rate or false positive rate) across these groups. Constraints of this form are susceptible to (intentional or inadvertent) fairness gerrymandering, in which a classifier appears to be fair on each individual group, but badly violates the fairness constraint on one or more structured subgroups defined over the protected attributes (such as certain combinations of protected attribute values). Individual notions of fairness avoid this problem, but at the cost of needing to make often unrealistic assumptions about the setting. We propose instead to demand statistical notions of fairness across exponentially (or infinitely) many subgroups, defined by a structured class of functions over the protected attributes. We will show how to achieve this in polynomial time, under the assumption that we are given oracles for solving the unconstrained learning problems (for both the set of classifiers to be learned, and the set of subgroups to be protected). Our algorithm casts the problem as solving for an equilibrium in a zero sum game, and observes that learning oracles are enough to efficiently play no-regret learning dynamics. We then demonstrate experimentally that our proposed algorithms are practical, by investigating their performance on several real datasets when instantiated with learning heuristics in place of oracles.
This talk is based on joint work with Michael Kearns, Seth Neel, and Steven Wu.
Speaker: Omer Reingold
Title: On Algorithmic Fairness Between Groups and Individuals 
Abstract: As algorithms increasingly inform and influence decisions made about individuals, it is increasingly important to address concerns that these algorithms might be discriminatory. Historically, definitions of fairness fell into one of two extremes: (1) broad-strokes statistical guarantees; (2) individual-level protections. Statistical guarantees tend to be much easier to satisfy (information and complexity theoretically), but tend to be much weaker in the protections they provide. We will discuss two recent works towards bridging the gap between statistical and individual protections. These works provide efficient learning algorithms that also ensure every subpopulation within some rich class is protected (according to some fairness notion).
One of the notions we will discuss is that of multicalibration — a new measure of algorithmic fairness that aims to mitigate concerns about discrimination that is introduced in the process of learning a predictor from data. The second notion studies fair classification within the versatile framework of Dwork et al. [ITCS 2012], which assumes the existence of a metric that measures similarity between pairs of individuals. Unlike previous works on metric-based fairness, we study the setting where a learning algorithm does not know the entire metric, but can query similarities between particular pairs of individuals a bounded number of times. We note that we do not make any assumption on the metric and are still able to obtain meaningful protection from systemic discrimination that we refer to as “metric multifairness.”
The talk will be focused on the various ways in which algorithmic fairness can be defined but will also elude to some of the ways in which it can be obtained. It is based on joint works with Úrsula Hébert-Johnson, Michael P. Kim and Guy Rothblum.
Speaker: Nicole Immorlica
Title: Fair Classification and Learning
Abstract:  Classification, learning, and optimization algorithms are increasingly used to make decisions of social consequence. An automated resume reader classifies applicants, deciding which are worth interviewing. A learning algorithm estimates the impact of a drug on health outcomes. A facility location algorithm chooses where to locate new warehouses. For these algorithms to be useful, practitioners strive to maximize their accuracy and optimality. However, this can result in differential treatment across population subgroups, resulting in a sense of inequity. Fairness metrics are used to measure the degree of inequity. In this talk, we explore how to jointly optimize fairness and accuracy using, as a black box, existing algorithms that optimize accuracy or optimality. Our first solution is tailored to classification tasks and proposes decoupling the classification task, using different classifiers for each subgroup. Our second solution can optimize any smooth and continuous function of accuracy and fairness in classification, learning, and optimization settings. It further has the advantage that subgroup membership, while used to train, is not used at run time. This additional power comes with the cost of added computational complexity in training.

Saturday, June 9, 2018

Gaming the Affordable Care Act (ACA)

One of the big lessons of market design is that participants have big strategy sets. Here's a new paper that explores some of what that has implied about how the Affordable Care Act is gamed by some participants.

Take-Up, Drop-Out, and Spending in ACA Marketplaces

Rebecca DiamondMichael J. DicksteinTimothy McQuadePetra Persson

NBER Working Paper No. 24668
Issued in May 2018
NBER Program(s):Health CarePublic EconomicsIndustrial Organization 
The Affordable Care Act (ACA) established health insurance marketplaces where consumers can buy individual coverage. Leveraging novel credit card and bank account micro-data, we identify new enrollees in the California marketplace and measure their health spending and premium payments. Following enrollment, we observe dramatic spikes in individuals' health care consumption. We also document widespread attrition, with more than half of all new enrollees dropping coverage before the end of the plan year. Enrollees who drop out re-time health spending to the months of insurance coverage. This drop-out behavior generates a new type of adverse selection: insurers face high costs relative to the premiums collected when they enroll strategic consumers. We show that the pattern of attrition undermines market stability and can drive insurers to exit, even absent differences in enrollees' underlying health risks. Further, using data on plan price increases, we show that insurers largely shift the costs of attrition to non-drop-out enrollees, whose inertia generates low price sensitivity. Our results suggest that campaigns to improve use of social insurance may be more efficient when they jointly target take-up and attrition.

Friday, June 8, 2018

Parag Pathak interview on designing theories for the real world

Here's the introduction, click on the link to read more, or to hear the audio recording.

Designing theories for the real world
The AEA interviews 2018 John Bates Clark Medalist Parag Pathak.
by Chris Fleisher

He’s been hailed for pushing the boundaries of market design theory while making it practical to real-world situations.
Parag Pathak is this year’s winner of the John Bates Clark Medal. The 37-year-old MIT professor has worked to improve the assignment of students to public schools, notably in Boston, and also evaluated the impacts of school choice systems on student outcomes.
And while his theoretical work has won him widespread praise, he says his engineering-oriented approach to economics has helped him figure out which problems are of greatest practical importance.  
The AEA spoke with Pathak about his research, the influence of his mentor and former AEA president Al Roth, the criticisms against economic theorists, and the opportunities to shape public policy.
An edited transcript follows and the full-length interview can be heard by clicking on the media player..."

Thursday, June 7, 2018

Salaries of new lawyers at big law firms are on the move

After a long period of stagnation, salaries of lawyers in associate positions at large law firms recently started to move, and are climbing (probably in lockstep) once again.

Above the Law has the story:
New York To $190K — No, Cravath Didn’t Make The First Move
The next associate salary war is beginning.

and here:
Salary Wars Scorecard: Which Firms Have Announced Raises? (2018)

and here

The Billion-Dollar Biglaw Firms That Have NOT Raised Associate Salaries





See earlier posts:

Sunday, July 3, 2016

Wednesday, June 6, 2018

Tuesday, June 5, 2018

Airbnb in Paris

The FT has an informative story about Airbnb's large footprint in Paris, the nuanced effects this has on the city, and French attempts at regulation:

 Airbnb: ‘It’s a cash machine. It’s magical. You are paid to go on holiday’

"The home-sharing site’s number one destination is Paris, where it stands accused of driving up rents and house prices"

Monday, June 4, 2018

The job market(s) for professional psychologists: history and current issues

Various parts of the psychology job market resolved problems of thickness, congestion and incentives by adopting centralized clearinghouses. For other parts of the job market, those issues persist. Here's a recent article, and some snippets from it regarding this history.

Recruitment and selection in health service psychology postdoctoral training: A review of the history and current issues. 
Bodin, Doug; Schmidt, Joel P.; Lemle, Russell B.; Roper, Brad L.; Goldberg, Robert W.; Hill, Kimberly R.; Perry-Parrish, Carisa; Williams, Sharon E.; Kuemmel, Angela; Siegel, Wayne.
Training and Education in Professional Psychology © 2017 American Psychological Association

2018, Vol. 12, No. 2, 74 – 81

"Pursuing a career in health service psychology involves navigating three broad stages of training: graduate school, doctoral internship, and postdoctoral training. Each stage involves distinct procedures for recruitment and selection. The purpose of this article is to review the history of and current issues involved in the recruitment and selection process for postdoctoral training in health service psychology. In this review, we will discuss the specialty of clinical neuropsychology separately as that specialty has a formal computerized match and therefore faces subsequent challenges that are distinct from, but in some ways mirror, the  faced broadly by health service psychology postdoctoral training programs.

...
"The current computerized matching psychology internship selection process began in 1998–1999, 10 years after an earlier trial, rejection, and reintroduction (Keilin, 2000). Prior to the introduction of computerized matching, the internship selection process relied on the “uniform notification day” (UND) system for more than 25 years. This process of internship offers and acceptances shortened from an initial offer and acceptance period of 9 days to 4 hours (Keilin, 1998). In 1988–1989, there was a trial period to evaluate the effectiveness of a computer-based algorithm match process. Although the outcomes showed a significant improvement over the UND, there was a lack of full participation by internship sites that appeared to have a detrimental impact on the outcomes observed (Keilin, 1998). Recurrent discussion within the Association of Psychology Postdoctoral and Internship Centers (APPIC) reflected gradually shifting approval, from a vote of 55% to 45% to retain the UND in 1990, to 77% approval to move to a computer-based match system by May 1998 for immediate implementation for the 1998–1999 recruitment year.
...
"There were wide-spread reports of both applicants and programs accepting less preferred choices due to the fear of not securing or filling a position within the UND window. APPIC responded by clarifying the rules with a prohibition against sites soliciting rank information (Constantine & Keilin, 1996). APPIC voted to proceed with a computer-based match process in 1998 using a match algorithm similar to the National Residency Match Program (Roth & Peranson, 1999). The computer-match system transcends difficulties on both sides by providing an equitable solution designed to provide the best possible match for all parties involved (Keilin, 1998). This solution reduces the pressure associated with short decision-making times and has the benefit of reducing the gridlock associated with UND (Roth & Xing, 1997).
...
"The computerized match has been used every year since, and it is now widely considered the optimal process for doctoral internship selection.

"The recruitment and selection process at the postdoctoral level remains in an evolutionary stage at the present time. Coordination of the psychology postdoctoral selection market is complicated by the fact that it is actually made up of multiple submarkets. Psychology interns may consider several options for their next professional experience, including an entry-level job, a research fellowship, a general clinical psychology fellowship, or a postdoctoral fellowship in a specialty practice area (e.g., neuropsychology, health psychology, clinical child psychology, or forensic psychology). Several of these submarkets have different timelines. For example, entry-level jobs and research fellowships are dependent on idiosyncratic funding streams and employment needs and, as such, may not realistically be expected to adhere to a coordinated timeline. 

...
"In 2003, there was renewed effort to establish more systemization to protect applicants from being forced into making decisions about early offers that did not reflect their true preferences. 
...
"As part of a 2009 APPIC biennial conference presentation, Lemle proposed a modified selection process with an additional feature intended to make participation more attractive to programs. The additional feature would allow applicants who received an early offer from a nonparticipating site to contact a preferred program to pledge they would accept a “reciprocal offer” should one be extended. A UND with reciprocal offer option (UNDr) assured programs that their top applicants who also wished to come to their site would not be lost to competing offers.
...
" Beginning in Fall, 2016, the APPIC postdoctoral workgroup took strides to address several proximal recommendations borne in the summit. First, the workgroup further refined the Postdoctoral Selection Guidelines (PSG) for positions starting in 2017–2018 as a step toward developing a clear and transparent system that would allow applicants sufficient time to consider offers (applicants were allowed 24 hr to consider offers) and allow programs the time needed to interview applicants. A primary aim of the PSG is to decrease the significant stress on both applicants and training directors. The PSG address multiple stages of the selection process impacting trainees including reasonable interview notification timing, consideration of remote interview formats, postponing offers until the UND, and proper use of the reciprocal offer option (UNDr).
...
"The APPIC postdoctoral workgroup also followed the summit recommendation to spearhead the development of a centralized listing of postdoctoral positions, the Universal Psychology Postdoctoral Directory (UPPD), that is free for both APPIC and non-APPIC member programs. 
...
"Clinical neuropsychology has a distinct history that is informative when considering the issues discussed in this article. Most notably, there is currently a formal computerized match for postdoctoral selection in clinical neuropsychology (Belanger et al., 2013; Bodin, Roper, O’Toole, & Haines, 2016). Prior to 1994, there was no organized process for recruitment and selection in clinical neuropsychology. 
...
"In 2001, APPCN partnered with NMS to conduct a computerized match for postdoctoral selection in clinical neuropsychology that has continued to the present day. The APPCN match employs the same algorithm used for the psychology internship match, but dissimilarities across the two recruiting environments have contributed to differences in the success of the two systems over the years. Since its inception, the internship match has enjoyed virtually universal participation by programs. Importantly, the APPCN match was introduced without a clear understanding of the total universe of positions being offered by neuropsychology postdoctoral programs, and those outside of APPCN were not a part of an organized group interested in centralized recruitment. Years later, Belanger et al. (2013) estimated that roughly two thirds of available positions were offered in the APPCN match. Withdrawal rates for applicants initially registering for the APPCN match have ranged from 26% to 37% over the past 10 years and have been stable from 34 and 36% for the last five years. Although some applicants withdraw for personal reasons, the most common reason has been to accept offers from independent programs prior to the rank-order list (ROL) deadline for the APPCN match.

Sunday, June 3, 2018

Repugnant markets on the radio



Repugnant Markets on the radio: I'll join Ken Taylor and Debra Satz on Philosophy Talk today, June 3


"We might ban buying or selling horse meat in the US not for the protection of horses, but because we find it morally repugnant. Yet this moral repugnance is clearly not universal, and on some level may even be arbitrary, given France's attitude toward horse meat. What role, if any, should moral repugnance play in determining the rules of our marketplaces? Even if we want to eliminate the influence of moral repugnance, can we? Debra and Ken hold their noses with Al Roth from Stanford University, author of Who Gets What ― and Why: The New Economics of Matchmaking and Market Design."

Get Philosophy Talk

Radio

Sunday at 11am (pacific) on KALW 91.7 FM Local Public Radio, San Francisc
Ken wrote thoughtfully about this yesterday on the Philosophy Talk blog:
REPUGNANT MARKETS,  Ken Taylor
*************
Update: and here we are at KALW:
Ken Taylor, Debra Satz, and Al Roth in the studio at Philosophy Talk
https://pbs.twimg.com/media/DeyV20-VQAAApPH.jpg 
And here's a link to a recording of the show:

Repugnant markets: listen to my Philosophy Talk chat with Ken Taylor and Debra Satz

Saturday, June 2, 2018

The Economist on blood plasma

The Economist comments on Canada's repugnance towards paying Canadians to donate blood plasma (when you can buy as much as you need from U.S. donors..see previous posts.)

Vital fluids
America’s booming blood-plasma industry
Paid-for plasma is both less exploitative than often recognised, and invaluable

"The World Health Organisation lists immunoglobulins and coagulation factors—both plasma-derived products—as essential medicines. Yet poor countries are often desperate for them and rich countries rely on American imports. Without financial incentives, supplies are hard to come by. “It’s not in people’s nature”, says Mr From, “to let a phlebotomist poke a needle in your arm and suck your blood out.”
**********

Vein attempts
Bans on paying for human blood distort a vital global market
The market in life-saving blood-plasma products depends on Americans who are paid for it

"The global demand for plasma is growing, and cannot be met through altruistic donations alone. Global plasma exports were worth $126bn in 2016—more than exports of aeroplanes. But paid plasma raises ethical, social and medical concerns: that it will lead to health catastrophes, as in the 1980s when tainted blood spread HIV and hepatitis; that it exploits the poor; and that it reduces the supply of “whole” blood, which is almost all donated voluntarily.

"None of these worries is well-founded. But Canadian reservations about paid plasma are shared across most of the world. America, China, parts of Canada and some European countries are among the few places that permit it. Those countries are extremely effective in securing supplies: three-quarters are collected in America alone, and another 10% in China, Germany, Hungary and Austria, where payment is also allowed. Of over 1,000 plasma-collection centres worldwide, 700 are in America. Jan Bult, head of a trade association representing companies that manufacture more than half of the world’s plasma products, says none collects plasma in countries that have banned compensation.

"Only countries that pay for plasma are self-sufficient in it. (Italy, where donors are given time off work, is close to self-sufficiency.) Half of America’s plasma is shipped to Europe—20m contributions-worth. Canada imports 80% of its plasma products from America. Australia imports 40% of its plasma products, too.

"Drug firms from countries that have banned pay-for-plasma do much of their collection in America. Three of the largest collection companies are European: Grifols of Spain, Shire of Ireland and Octapharma of Switzerland. The parent company of another big collector, CSL Behring, is Australian. Together these four firms run nearly eight out of ten plasma-collection centres. Some of their manufacturing capacity is in America, but much is located elsewhere. Switzerland, which collects very little plasma, exported $26bn-worth of plasma products in 2016.

...

It remains legal to pay for whole-blood donation in America today. But hospitals refuse to accept it. Today’s plasma, however, is safe from the contamination risks of the past. Modern screening and sanitisation are extremely effective. Graham Sher, chief executive of Canadian Blood Services, a non-profit, says plasma products from paid donors are “as safe as those from our unpaid donors”.

Other prejudices against pay-for-plasma are equally deep-seated. Some data, for example, lend weight to the suspicion that it preys on the poor. American plasma centres are concentrated in less well-off bits of the country. Typically they are in postal districts where 27.4% of the population are poor, according to The Economist’s analysis of census data. This is much higher than the average American poverty rate of 16.5%.

The other worry, shared by Dr Sher, is that paying for plasma may lead to a reduction in whole-blood donation. But, if that were true, the problem would be intensifying, as pay-for-plasma centres have nearly doubled worldwide in the past five years. But Peter Jaworski, of Georgetown University, is sceptical, suggesting that, anecdotes aside, the evidence shows paid plasma donation “does not crowd out voluntary blood-donation”. Americans, for example, continue to donate as much voluntary blood per head as do Canadians.

The aversion to paid-for plasma carries its own risks. According to Grifols, the geographic imbalance puts supplies of plasma products at risk. At the plasma industry’s main annual conference, held this year in Budapest in March, over-reliance on imports from America was a hot topic. Representatives from several countries (including Canada) recognised they must do more to diversify their supplies. Making it legal to pay for plasma is an obvious first step."

This article appeared in the International section of the print edition under the headline "Thicker than water"
 Print edition | International
May 10th 2018
*************

And here's a letter to the editor https://www.economist.com/letters/2018/06/02/letters-to-the-editor. (The highlighted sentence seems to reflect that the editor who decides what letters to publish is a different person than the economics editor  who writes that I study repugnance only to dismiss it, and whose views I remarked on here and here.)

"In your series of articles advocating for payments to plasma donors, you stress the positive supply effects that payments may have. Appeals to increased efficiency, however important, are unlikely to persuade politicians and the public when the opposition to payments resides in deep-rooted ethical concerns. Starting with the seminal work of Nobel laureate Alvin Roth, economists have begun to seriously consider how to design effective market mechanisms while respecting moral beliefs, in order to reach a virtuous balance in the trade-offs between morality and efficiency.

"Based also on our own research on ethically contentious transactions, we would suggest that policymakers collect two types of evidence before adopting extreme policies such as outright bans. First, pilot projects would help assessing the impact of various policy options. Second, policymakers should inform the public about this evidence, and take into account the ensuing prevailing opinions and ethical concerns in the population, instead of being based on pressures (in one direction or the other) from vocal but often scarcely representative groups.

NICOLA LACETERA
University of Toronto
MARIO MACIS
Johns Hopkins University
Baltimore, Maryland 

Friday, June 1, 2018

Gratitude for an organ donation

Only a curmudgeon (and I know some) would think of this as (illegal) donor compensation.

Here's a story from the Greeley, Colorado Tribune

Labor of Love: Husband of former city councilwoman works to restore old car for kidney donor

Thursday, May 31, 2018

Kidney exchange takes another step forward in Mexico: Pro-Renal

My recent visit was to speak about kidney transplantation in Mexico, and to raise awareness of and support for the new kidney exchange network, Pro-Renal, which has already collaborated successfully with the Alliance for Paired Donation (APD).

Kidney exchange (and international cooperation for global kidney exchange) received a lot of favorable press, here are some reports.

In Forbes Mexico:


Cada año mueren 7 millones por falta de un trasplante de riñón: Alvin E. Roth
Para el Premio Nobel, las barreras que impiden un trasplante renal deberían ser derribadas, porque los tratamientos más costosos son también los que rezagan los mejores resultados.
Jessica Martínez, mayo 23, 2018
[Google Translate: Every year 7 million die in the absence of a kidney transplant: Alvin E. Roth  ... the barriers that prevent a kidney transplant should be demolished, because the most expensive treatments are also those that lag behind the best results."
***********
Anuncian campaña para duplicar el número de trasplantes renales en México
mayo 24, 2018


Rafael Pardo, Mike Rees, Al Roth, Marisol Robles, Arturo Dib Kuri
************
Llega a Mexico la nonacion renal pareada [Paired renal donation arrives in Mexico]
*************
**********
***********
Aplicarán algoritmo en México para hallar donantes de riñón
25/05/2018 05:31  XIMENA MEJÍA
*********


***************

Buscan salvar vidas con algoritmo para trasplantes [They seek to save lives with an algorithm for transplants]
************

 En México, con algorismos de compatibilidad se buscará donación de riñones

********


**********

Update: here's a story from an interview that must have been conducted during that visit that came out only in September:

ENTREVISTADOS • SEPTIEMBRE 17, 2018
Alvin Roth, Premio Nobel de Economía 2012

photos: Bruno Sánchez

Wednesday, May 30, 2018

Martine Quinzii, RIP

This sad news about Martine Quinzii comes from the Society for the Advancement of Economic Theory.


In Memoriam: Martine Quinzii
"Our friend and colleague passed away on May 25, 2018 after a long illness that she faced with both courage and dignity.
She was a central figure of the Mathematical Economics community, inspiring us by her powerful intellectual agenda, sharp presence in academic gatherings, and irresistible enthusiasm for the reach of General Equilibrium analysis. Her PhD thesis on the core in production economies and its decentralization by marginal cost pricing attracted early attention, and her 1984 analysis of assignment economies is the first general existence result in economies with indivisible goods and money. But her most influential contribution is to the analysis of financial markets, to which, with her husband Michael Magill, she devoted a quarter century of her immense energy. This culminated in their 2008 book on the theory of Incomplete Markets, which is widely acknowledged as the best reference on the topic. The book combines mathematical rigor, formal elegance and accessibility to non-specialists.  The most recent of Martine and Michael’s important contribution improves our understanding of the role of money in general equilibrium models with financial frictions. She was also a very talented lecturer and she had the ability to communicate complex ideas with passion, rigor, and clarity.
Martine studied at the Ecole Normale Superieure in Paris. She obtained her PhD in Mathematical Economics in 1986 and her Habilitation in 1988 at the University of Paris.  Before her departure to the US in 1986, she taught in Aix, Marseille, and Paris and was Research Associate at the Ecole Polytechnique. In the US part of her career, she taught at the University of Southern California from 1986 to 1995 and at UC Davis from 1995 to her retirement in 2016, and she chaired the Economics Department there from 1995 to 1999.
She was a Fellow of the Econometric Society since 2000, and an Economic Theory Fellow since 2011. She served as an Associate Editor of Econometrica, Economic Theory, Journal of Mathematical Economics, and several other academic journals.
We already miss her and our thoughts go to her family and to Michael Magill, her long term partner in economics and life.
May 29, 2018
Bernard Cornet, Hervé Moulin, and Jean-Charles Rochet"


Tuesday, May 29, 2018

Stanford Engineering celebrates Itai Ashlagi


Faculty Spotlight: Itai Ashlagi
Itai Ashlagi joined the MS&E faculty in 2015 to continue his intensive study of market design.

"He specializes in matching markets, such as kidney exchange programs, organ allocation, school choice, and the National Resident Matching Program.
"I can't think of a better intellectual environment for my research than MS&E, where the faculty and students share a common goal of designing systems and policies that impact our lives."

Monday, May 28, 2018

Protecting and Preserving Competition in Matching Markets--Antitrust and the Medical Match (video)

Here's a video of the talk I gave in Chicago in April, at an antitrust conference at the Stigler Center.  I used as my main example the anti-trust lawsuit that was brought in 2002 against the National Resident Matching Program (NRMP) (and all the hospitals that participated in it). I end with some more general discussion of computerized marketplaces. (My talk goes for a bit less than an hour, and the video continues for another ten or fifteen minutes of Q&A)




I intended to begin the talk with a video satire of the medical match, but wasn't able to show it due to technical problems, so I just spoke about it. But here it is for those of you who missed the Harry Potter version of the medical match:

Harry Potter and the Resident Match | ZDoggMD.com

Sunday, May 27, 2018

Ireland votes to repeal a constitutional ban on abortion

A vote in Ireland strikes down a consitutional ban on abortion, and will likely lead to legal abortions in at least some cases, and a reduction in black market and overseas abortions.

The NY Times has the story:
Ireland Votes to End Abortion Ban in Rebuke to Catholic Church

"DUBLIN — Ireland voted decisively to repeal one of the world’s more restrictive abortion bans, sweeping aside generations of conservative patriarchy and dealing the latest in a series of stinging rebukes to the Roman Catholic Church.

"The surprising landslide cemented the nation’s liberal shift at a time when right-wing populism is on the rise in Europe and the Trump administration is imposing curbs on abortion rights in the United States. In the past three years alone, Ireland has installed a gay man as prime minister and has voted in another referendum to allow same-sex marriage.
...
"The vote repeals the Eighth Amendment of the Constitution — a 1983 measure that conferred equal rights on the fetus and the mother and banned abortion under almost all circumstances. Before the referendum, the government had pledged to pass legislation by the end of the year to allow unrestricted terminations up to 12 weeks if the amendment was set aside.

"The outcome signaled the end of an era in which thousands of women each year had been forced either to travel abroad or to buy pills illegally online to terminate their pregnancies, risking a 14-year jail sentence.
...
"It was the latest, and harshest, in a string of rejections of the church’s authority in recent years.

"The church lost much of its credibility in the wake of scandals involving pedophile priests and thousands of unwed mothers who were placed into servitude in so-called Magdalene laundries or mental asylums as recently as the mid-1990s.
...
"Abortion supporters had campaigned heavily on so-called hard cases faced by women, such as rape or fetal abnormalities. The referendum result showed that many Irish voters agreed that women in those circumstances should be allowed a choice.

That shift in attitude was driven in part by prominent cases, such as the 2012 death of Savita Halappanavar, who had asked for a termination of her pregnancy but later died of complications from a septic miscarriage. Ms. Halappanavar’s face was printed on placards supporting abortion, and on Saturday morning people placed flowers in front of a mural of her face in Dublin.

“People started realizing that compassion didn’t fit just one side,” Ms. Reidy said.

Saturday, May 26, 2018

Update on the Orthopaedic Sports Medicine Fellowship Match

From the Orthopaedic Journal of Sports Medicine:
Outcomes in the Orthopaedic Sports Medicine Fellowship Match, 2010-2017
by Mary K. Mulcahey, MD*, Meghan K. Hayes, BS, Christopher M. Smith, MD, Matthew J. Kraeutler, MD, Jeffrey D. Trojan, BA, Eric C. McCarty, MD

"Together with an increase in the number of applicants for orthopaedic fellowships, the process of applying to fellowship programs has evolved over the past several years. Currently, the majority of orthopaedic fellowship programs utilize a centralized, formal matching process.2 Sports medicine fellowship programs utilized the National Resident Matching Program until 2005.2 After the discontinuation of the formal matching process, residents were often asked to commit to a position during their third year of residency, before receiving adequate exposure to all subspecialties, or they were forced to accept or reject an offer before they could compare programs.
...
"A recent study assessed the match process and the Accreditation Council for Graduate Medical Education (ACGME) status of fellowships in the 9 orthopaedic subspecialties (adult reconstructive orthopaedics, foot and ankle orthopaedics, hand surgery, musculoskeletal oncology, orthopaedic sports medicine, orthopaedic surgery of the spine, orthopaedic trauma, pediatric orthopaedics, and shoulder and elbow surgery).3 This study discovered that 25% of available orthopaedic fellowship positions are devoted to sports medicine.3,12 Sports medicine is also the most popular orthopaedic subspecialty among current AAOS members, with the percentage of members who completed a sports medicine fellowship rising from 27% in 2004 to 49% in 2010.16 Additionally, orthopaedic sports medicine was found to have the highest proportion of ACGME-accredited fellowship programs, with 93.1% of programs and 97.3% of positions receiving accreditation.
...
:A 2014 study by Daniels et al3 investigated orthopaedic subspecialty fellowships in terms of the match process, characteristics, and ACGME accreditation. Fellowships were assessed by searching subspecialty society webpages and individual program websites. This study found that among the 9 orthopaedic subspecialty fellowships, there were collectively more positions offered than there were graduating orthopaedic residents.3 In 2013, there were 792 allopathic and osteopathic resident graduates and 897 total fellowship positions.3 The current study demonstrates that the opposite trend exists for applicants to sports medicine fellowships. In each year, excluding 2014, there were more sports medicine fellowship applicants than positions available."
***********
See my previous posts on orthopaedics, most of which are about the fellowship match.

Friday, May 25, 2018

Some adult supervision of the law clerk hiring process


Kagan Says She'll 'Take Into Account' Whether Judges Follow New Clerk Hiring Plan

"U.S. Supreme Court Justice Elena Kagan recently threw her support behind the new law clerk hiring plan by saying she will “take into account” in her own hiring whether judges and law schools comply with the new process
...
"Kagan’s message for her own chambers is likely to be heard coast to coast. In her nearly eight years on the high court, Kagan has hired clerks largely from the D.C. Circuit but also from the Fourth, Sixth and Ninth circuits and from judges across the ideological spectrum.

A former Harvard Law School dean and professor, Kagan is in a position to understand the effect on students of the former hiring process in which first-year students faced pressure to make clerkship commitments and law professors make recommendations “on less and less information,” Morrison said."
***********
see my earlier post

Tuesday, March 6, 2018



HT: Kim Krawiec

Thursday, May 24, 2018

Gambling and Sports

A class of repugnant transactions (gambling, subject to many legal restrictions designed to limit its availability) and  protected transactions (sports events, subject to many regulations designed to protect their integrity) have come a bit closer together through a recent Supreme Court decision about a complicated law.

Here's the news story from Inside Higher Ed:
Gambling on Sports Legal
The Supreme Court has opened the way for states to legalize betting on athletics, a defeat for the National Collegiate Athletic Association and professional leagues.

"The U.S. Supreme Court on Monday struck down a law that had forbidden gambling on college and professional sports outside Nevada."

The link above goes to the Supreme Court decision.
But what makes the law that they struck down complicated is that it didn't make sports betting a crime, rather it forbade States from allowing it.

Here's some legal commentary on the decision from a law firm involved in the case:
https://www.gibsondunn.com/supreme-court-strikes-down-federal-limits-on-sports-gambling/

"The Supreme Court held 7-2 that a federal law prohibiting States from authorizing sports betting violates the Tenth Amendment because it impermissibly commandeers state legislatures.

"Background: A federal law – the Professional and Amateur Sports Protection Act of 1992 (PASPA) – prohibits States from authorizing or licensing sports gambling.  In 2014, the New Jersey legislature repealed existing prohibitions on sports gambling at casinos and racetracks.  The NCAA and the four major professional sports leagues sued the State, arguing that the decision to allow sports gambling violated PASPA.

"Issue: Whether PASPA’s federal prohibition on state authorization of sports gambling violates the Tenth Amendment because it commandeers state legislatures.

"Court’s Holding: Yes.  PASPA unconstitutionally commandeers state legislatures by dictating the content of state law regarding sports gambling (i.e., preventing States from legalizing sports gambling).

“A more direct affront to state sovereignty is not easy to imagine.”

***********
Here's the Volokh conspiracy on possible broader implications of this decision

Broader Implications of the Supreme Court's Sports Gambling Decision
Commentators are right to suggest that Murphy v. NCAA will help sanctuary cities, but wrong to claim it is like to undermine federal laws restricting state taxes.

Wednesday, May 23, 2018

Still bleeding for Canada

Here's a paper on the ongoing debate in Canada about whether it should be legal to pay plasma donors.

Moral NIMBY-ism? Understanding Societal Support for Monetary Compensation to Plasma Donors in Canada
by
Nicola Lacetera, Mario Macis
NBER Working Paper No. 24572 May 2018

Abstract: "The growing demand for plasma, especially for the manufacture of therapeutic products, prompts discussions on the merits of different procurement systems. We conducted a randomized survey experiment with a representative sample of 826 Canadian residents to assess attitudes toward legalizing payments to plasma donors, a practice that is illegal in several Canadian provinces. We found no evidence of widespread societal opposition to payments to plasma donors. On the contrary, over 70% of respondents reported that they would support compensation. Our Canadian respondents were more in favor of paying plasma donors elsewhere than in Canada, but the differences were small, suggesting a weak role for moral “NIMBY-ism” or relativism. Moral concerns were the respondents’ main reason for opposing payments, together with concerns for the safety of plasma from compensated donors, although most of the plasma in Canada does come from paid U.S. donors. Among those in favor of legalizing payments to donors, the main rationale was to guarantee a higher domestic supply. Finally, roughly half of those who declared to be against payments reported that they would reconsider their position if domestic supply plus imports did not cover domestic demand. Most Canadians, therefore, seem to espouse a consequentialist view on issues related to the procurement of plasma.