The American Kidney Fund, in the NY Times, and riposte from the AKF

In a nuanced back and forth, the NY Times has suggested that the American Kidney Fund is abusing its status as a charity for patients who can't otherwise afford dialysis by only encouraging applications from patients at clinics which contribute to the AKF. They reply that this isn't the case.

Here's the NY Times story: Kidney Fund Seen Insisting on Donations, Contrary to Government Deal

"The American Kidney Fund is one of the largest charities in the country, with an annual budget of over $250 million. Its marquee program helps pay insurance premiums for thousands of people who need dialysis, a lifesaving and expensive treatment for kidney failure.

"The organization has earned accolades for its efficient use of the money.

"Under an agreement with the federal government, the Kidney Fund must distribute the aid based on a patient’s financial need. But the charity has resisted giving aid to patients at clinics that do not donate money to the fund, an investigation by The New York Times has found. The actions have limited crucial help for needy patients at these clinics. The agreement governing the relationship between the group and the companies forbids choosing patients based on their clinic."

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Here's the AKF's response: Our response to Sunday’s New York Times article

"An article in the business section of Sunday’s New York Times presented a factually incorrect and unfair picture of the American Kidney Fund (AKF) and the lifesaving work that we do through our Health Insurance Premium Program (HIPP). We have reached out to the Times to request corrections on the most serious factual errors and misleading statements. In the wake of this article there are several key points that we feel are essential to emphasize:

• Since we are a charitable organization, we do ask all providers to contribute to our program—but we never require it.
• We have never turned away a patient who is financially qualified to receive a grant, and we never will turn away such a patient.
• We never condition our issuing of grants on whether a provider has contributed to AKF, and fully 40 percent of dialysis providers with patients receiving help from AKF don’t contribute anything to AKF.  
• There is no “earmarking” of donations.
• HIPP has firewalls in place to protect the integrity of the program."

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The agreement linked to in the NY Times article (to put it in context) is  Advisory Opinion No. 97-1  of the Office of Inspector General of the U.S. Department of Health & Human Services.

Living donor advocate Sigrid Fry-Revere has an updated proposal

Sigrid Fry-Revere writes to me about her updated living donor proposal:
"The big advantage of this proposal are as follows: 1) It helps those in need of organs who need help most — those at the front of the waiting list. These people, if they had a way of finding a living organ donor on their own, would have done so before they made it to the front of the waiting list 2) It follows the distributive justice model of the original NOTA and UNOS design (same as for deceased donation — help those in most need first). 3) Because it doesn’t help everyone, it is much more affordable (possibly even saves money within the first year instead of just 5 or 10 years down the line). 4) It can be phased in without creating a whole new bureaucracy because it includes incentives for OPOs to do the work.  And, 5) perhaps most importantly, this proposal could be implemented under the current law through regulation.  It could be done by Congress, but does not require an act of Congress."

You can find it here: The Save Lives, Save Money Now! Proposal Specifics and Background

The highlights:
"Specific Elements: • Follow original intent of NOTA and have Medicare help patients in greatest medical need first and according to UNOS current wait list criteria by:
(a) paying expenses of donors willing to give to top match in their region, and
(b) paying the Organ Procurement Organizations (OPOs), which currently
match deceased donor organs with recipients, to arrange living matches as
well.
• Create living donor registry that allows donors at any time after their donation to put themselves AND / OR one relative to the front of the list in the region where the recipient lives (e.g. voucher system, but national. Waiting list points to be determined by UNOS)."
*************

Here is her organization's home page: http://www.helplivingdonorssavelives.org/ and here is another: http://www.stoporgantraffickingnow.org/

Repugnance watch: Wedgwood vase could be saved from export after culture minister intervenes

Can cultural treasures be sold to foreign buyers?  The Telegraph has the story:
 Wedgwood vase could be saved from export after culture minister intervenes

"The black “Basaltes” vase was put on sale at Christie’s in July by Anne Makeig-Jones, a descendant of Wedgwood.
...
"The decision to defer the export licence follows a recommendation by the Reviewing Committee on the Export of Works of Art and Objects of Cultural Interest, administered by the Arts Council."
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See my earlier post: Market for (smuggled) cultural treasures

U.S. Renal Data System 2016 annual report (data for 2014)

USRDS 2016 annual report
This year’s report provides data from 2014

highlights from the report include:

• There were 120,688 newly reported cases of end-stage kidney disease, representing a slight increase of 1.1 percent compared to 2013. At the end of 2014, there were 678,383 dialysis and transplant patients receiving treatment for end-stage kidney disease, up 3.5 percent from 2013.
• Among all patients who currently receive hemodialysis, use of an arteriovenous fistula, a surgically created vein used to remove and return blood during dialysis, since 2003, has increased from 32 percent to 63 percent. Arteriovenous catheter use has also declined from 27 percent to 18 percent during this period.
• Medicare spending for beneficiaries ages 65 and older who have chronic kidney disease exceeded $50 billion, representing 20 percent of all Medicare spending in this age group. Total Medicare fee-for-service spending in the general Medicare population increased by 3.8 percent in 2014 to $435.6 billion, with $32.8 billion, or 7.2 percent, of that overall spending accounting for end-stage kidney disease patients. Compared to 2013, the costs of Part D claims and skilled nursing facility care in 2014 grew at the fastest rates of 21 percent and 5.5. percent, respectively.
• Prior to 2013, Medicare spending on hospice care in end-stage kidney disease patients had been experiencing one of the highest rates of growth of any category of Medicare spending, but this spending declined by 6.3 percent in 2014.
• As of December 31, 2014, the kidney transplant waiting list increased by 3 percent over the previous year to 88,231 candidates, of which 83 percent were awaiting their first kidney transplant. With less than 18,000 kidney transplants performed in 2014, the active waiting list was 2.8 times larger than the supply of donor kidneys.

“An interesting note on kidney transplants is a relatively recent initiative called kidney paired donation,” Saran says. “The initiative is aimed at increasing the availability of living donor transplants, and in its simplest form is essentially when two living donors do not match with the respective recipients and decide to perform an exchange whereby the donation goes to each other’s compatible recipient. Kidney paired donation transplants have risen sharply in recent years with 552 performed in 2014, representing 10 percent of living donor transplants that year.”

Matchmaking nudges and noodges in the internet age

The internet dating site JSwipe has a program called ParentPay. The website has a banner reading (subtly) "We want grandchildren."

Here's the text of the ad that made its way into my email:

"Hey Mom, Hey Dad,

Hanukkah is here! We have the perfect gift. 

We both know your kid is a catch and anyone would be lucky to date them. It's time to give your son or daughter (friend, cousin, or grandkids) the right tools for finding *Jewish* love in the digital age --- and fast track your way to grandkids.

JSwipe is the #1 Jewish dating app with nearly one million users across the world. We're responsible for hundreds of marriages and want your kids to be next! Really. That's our job.

JSwipe offers a First Class membership that provides premium features to maximize the impact of their dating experience. Better matches = better dates. While their unpaid internship is great for their career, it's not so great for helping them afford a First Class membership.

That's where you come in!

Because you're such incredible parents, we're offering you the opportunity to gift your child one-year of JSwipe First Class for $99, less than half of what it usually costs! Consider it their "love allowance." The perfect Hanukkah gift! The gift of love that keeps on giving.

Would you be happy to have a new guest at your next family holiday? We know Bubbe would. Don't Passover this opportunity! "
*************

JSwipe has a free mode and a paid mode, and the paid mode gives more signals (superswipes) that can be sent per day, etc.  Here's a review

The Vatican celebrates Frank Delmonico

Here's the (November 29th) announcement from the New England Organ Bank:
We are very proud to announce that New England Organ Bank's Chief Medical Officer, Dr. Francis Delmonico, was inducted into the Pontifical Academy of Sciences this week.
"With this lifetime appointment, he becomes one of just 70 leaders in the field of science today to have this honor. Among other members are theoretical physicist Stephen Hawking and Human Genome Project founder Francis Collins. In addition to his long career as a kidney transplant surgeon, Dr. Delmonico leads the World Health Organization's efforts to prevent transplant tourism and organ trafficking."

Here's Frank's page at the Pontifical Academy: Francis L. Delmonico

Here's a photo he sent me:

Kidney exchanges within a single transplant center

In the emerging ecology of kidney exchange in the U.S., there are more and more exchange transplants that are  "internal" exchanges among the patient-donor pairs of a single transplant center..

Here's a recent news story that's indicative of that:
The first internal paired kidney exchange completed at LLUMC, chain started by altruistic donor-- Two adults now have a longer, healthier life ahead of them thanks to two complete strangers.

"The first internal paired kidney exchange was successfully completed at Loma Linda University Medical Center (LLUMC) late last month.

"The chain began with an altruistic donor from Orange County who gave a kidney to an individual from the Inland Empire. That recipient had a donor that was not a compatible match and was able to give to another individual in need of a kidney. The four surgeries took place Monday, Nov. 28.

...

"Living-donor chains have the potential to dramatically reduce transplant waiting times for thousands of patients,” said Rafael Villicana, MD, a transplant nephrologist and the medical director of the kidney transplant program at Loma Linda University (LLU) Transplantation Institute. "This is the best way for patients with incompatible donors to be transplanted quickly and achieve the best results."Having a living donor can eliminate the wait. But in one-third of such cases, a transplant can't be done because the immune systems of the patient and a willing donor don't match.

"Each chain begins when an altruistic person steps forward to donate a kidney, expecting nothing in return.

"While Loma Linda has been involved in other kidney exchanges, this is the first that was all done in house.

"Approximately 130 kidney transplants are performed at LLUMC annually."

Early admissions continues to grow at Harvard and elsewhere

The Harvard Gazette reports: 938 admitted early to College Class of 2021
Early action is ‘new normal’ for undergraduate admissions, Fitzsimmons says

"Applications for early action at Harvard College rose 5 percent this year to 6,473, and 14.5 percent, or 938 students, were admitted to the Class of 2021. Last year, 6,167 applied early, and 14.8 percent, or 914 students, were admitted.

“Early admission appears to be the ‘new normal’ now, as more students are applying early to Harvard and peer institutions than ever before,” said William R. Fitzsimmons, dean of admissions and financial aid. “At the same time, we have continued to stress to applicants, their families, and their guidance counselors that there is no advantage in applying early to Harvard. The reason students are admitted — early or during the regular action process — is that their academic, extracurricular, and personal strengths are extraordinary.”

The admissions committee is careful to ensure that only those students who are, in Fitzsimmons’ words, “100 percent certain” to be admitted in regular action are admitted early. “This is particularly important because in recent years we have received record numbers of applications,” said Fitzsimmons. Last year, 39,041 students applied for admission to the Class of 2020. Ten years ago, 22,754 students applied for admission to the Class of 2010."
****************

Maybe the growth in early admissions is happening at Stanford too, but apparently we're not saying:
In break from past, Stanford declines to release early admissions data

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In the NY Times, Frank Bruni complains of the stress it causes the children of his friends: The Plague of ‘Early Decision’

NLDAC announces a trial of Lost Wages Reimbursement for Living Organ Donors (funded by the Arnold Foundation)

Here's some good news in an email that arrived yesterday from NLDAC, the National Living Donor Assistance Center (about which I have had several recent and not so recent posts).  Up until now, NLDAC has only been able to provide travel assistance to some means-tested kidney donors. The new trial will allow the effect on donation of also reimbursing lost wages.

Lost Wages Reimbursement for Living Organ Donors Trial Announced

FOR IMMEDIATE RELEASE Media Contact: Diane Mossholder 703-414-7870 diane.mossholder@asts.org   Arlington, VA – December 21, 2016: The National Living Donor Assistance Center (NLDAC) announces that it will conduct a randomized controlled trial that will assess the impact of interventions intended to remove financial barriers to living organ donation through wage reimbursement.  NLDAC was established in 2007 to administer a grant funded by the U.S. Health Resources and Services Administration to provide greater access to transplantation for persons who want to donate, but cannot afford the travel and subsistence expenses associated with donation. It currently provides travel and subsistence funds for nearly 1000 people per year who wish to become living organ donors to offset their expenses related to donation. Living donors usually travel at least three times to the transplant center and are required to stay near the hospital for up to two weeks after the transplant surgery for monitoring. They are unable to work during their donation and recovery time, and the loss of wages can be a significant financial barrier. This study will provide data to help answer the question of whether removing that barrier increases living donation in the United States. The Laura and John Arnold Foundation provided funding for the trial, which will be administered by the American Society of Transplant Surgeons in partnership with the Arbor Research Collaborative for Health, with additional researchers from University of Arizona, the Wharton School of the University of Pennsylvania, and Mayo Clinic Arizona.  Five transplant centers with active living donor transplant programs will participate in the trial. “Removing financial disincentives to organ donation has long been a goal of ASTS,” said Timothy L. Pruett, MD, president of the American Society of Transplant Surgeons (ASTS). “I’m pleased that we are able to conduct this trial and gather data on the extent to which the prospect of lost wages discourages donors from coming forward or even being asked to consider donating. With more than 120,000 people waiting for an organ in the United States, we must do everything possible to ensure that those willing to donate are able to do so without financial harm to themselves or their families.” “Our study design – potential transplant recipients will be randomly offered or not offered wage reimbursement for their donors – incorporates a high level of scientific rigor,” noted Robert M. Merion, MD, president and CEO of Arbor Research Collaborative for Health. “When the study is completed, we will know much more about the role played by lost wages as a barrier to living organ donation, and the extent to which removal of that barrier leads to more living donor transplants and improved lives for patients. We are delighted that the Laura and John Arnold Foundation has recognized the societal importance of this question.” The trial will begin in 2017 and is projected to run through 2018. ### About NLDAC The National Living Donor Assistance Center (NLDAC) was established in 2007 to provide greater access to transplantation for persons who want to donate, but cannot otherwise afford the travel and subsistence expenses associated with donation. The program is funded by grant number U13HS07689 from the Healthcare System Bureau, Health Resources and Services Administration, U.S. Department of Health and Human Services. It is administered by the American Society of Transplant Surgeons, University of Arizona Health Sciences, Arbor Research Collaborative for Health, Washington University – Missouri, and Mayo Clinic – Arizona. For more information, visit LivingDonorAssistance.org.   About ASTS Established in 1974, the American Society of Transplant Surgeons (ASTS) is the oldest abdominal organ transplant society, serving approximately 1,800 surgeons, physicians, scientists, pharmacists, coordinators, and advanced transplant providers. ASTS is committed to fostering the practice and science of transplantation and guiding those who make policy decisions by advocating for comprehensive and innovative solutions to the needs of our members and their patients. ASTS is a nonprofit organization in Arlington, Virginia. For more information, visit ASTS.org. About Arbor Research Arbor Research Collaborative for Health is committed to improving patient care through research that shapes medical policies and practice. In particular, Arbor Research conducts health outcomes research on chronic disease and end-stage organ failure, with expertise in biostatistical analysis, clinical practice, health economics, public policy, database management and integration, and project coordination. Through research projects that are national and global in scope, Arbor Research’s scientific collaborations provide valuable and timely information to the worldwide health care community. A full description of the project portfolio is available at ArborResearch.org.   About the Laura and John Arnold Foundation LJAF is a private foundation that is working to improve the lives of individuals by strengthening our social, governmental, and economic systems. It has offices in Houston, New York City, and Washington, D.C. www.arnoldfoundation.org.

Organ donation and transplantation in Japan

The Chicago Tribune has an article (reprinted/translated?) from Japan:
Japan badly lags world in organ transplants
Yukiko Takanashi and Sakae Sasaki, (c) 2016, The Japan News/Yomiuri
(c) 2016, The Japan News/Yomiuri

"In July 2010, the revised Organ Transplant Law came into effect, enabling organ donations after the brain death of children younger than 15. However, there have been only 12 cases of organ donation by children under 15 since then. According to the Japanese Society for Heart Transplantation, 29 Japanese children under 18 traveled abroad for a transplant between 2010 and June 2016. That is more than twice the number that received a donor organ in Japan.

...

"In 2015, the organ donation rate in Japan stood at 0.7 people per million people. Spain had the highest rate at 39.7 people per million. The gap between Japan and other major countries remains wide. The rate stood at 28.5 people per million people in the United States, 27.5 in France, and 20.2 in Britain.

...

"The so-called Wada transplant, said to be Japan's first transplant from a brain-dead donor, was conducted in 1968 by Juro Wada at Sapporo Medical University. The boy who received the donor's heart died, and Wada was charged with murder. Questions were raised as to whether the organ donor had really been brain dead, and the case stirred a major controversy over the definition of death. For more than 30 years after that, no transplants from brain-dead donors were performed in Japan."
**************

Deutsche Welle has a related story:
Why organ transplant is so difficult to carry out in Japan
Restrictive laws, religious concerns and a lack of knowledge about donating organs mean that medically-sophisticated Japan lags well behind other nations in life-saving operations. Julian Ryall reports from Tokyo.

Ontario's new surrogacy law (and other laws regarding who is the parent of a child)

In Canada, Ontario has just (last month) amended some of its laws regarding the definitions of who are the parents of a child, with implications for surrogacy, among other things.
Bill 28 Projet de loi 28
An Act to amend the
Children’s Law Reform Act,
the Vital Statistics Act
and various other Acts
respecting parentage and
related registrations

Here's the part on surrogacy, which seems to imply that surrogacy in Canada will be subject to legal risk about who the parents are until the child is seven days old.

"7. Where a surrogate and one or more intended parents of
a child to be carried by the surrogate enter into a surrogacy
agreement and a child contemplated by the
agreement is born, the intended parents become the
parents of the child and the surrogate ceases to be a
parent of the child if specified conditions are met.
These conditions include that there are no more than
four intended parents under the agreement, that each of
the parties to the agreement received independent legal
advice before signing, and that the child is conceived
through assisted reproduction. The change in parentage
is also contingent on the surrogate giving written consent
relinquishing the surrogate’s entitlement to parentage
of the child, but the consent may not be given
before the child is seven days old. Until that time, after
the child is born the surrogate and the intended parents
share parental rights and responsibilities respecting the
child, unless the surrogacy agreement provides otherwise.
If the surrogate does not or cannot give consent,
an application may be made to the court for a declaration
of parentage respecting the child. Although a surrogacy
agreement may be used as evidence of parental
intent, it is unenforceable in law. (Section 10)"
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Here is some commentary on that and other parts of the law, from the blog Above the Law:
Ontario’s New Surrogacy And Sperm Donation Law Is Both Awesome And Terrible

Crowdfunding For IVF

NPR has a story which involves a combination of very modern transactions:
Please, Baby, Please: Some Couples Turn To Crowdfunding For IVF

"They began with a less costly and less invasive option: IUI or intrauterine insemination. That's where sperm is inserted with a catheter directly into the woman's uterus at the time of ovulation. The procedure costs, on average, just under $1,000 a try.
...

"The next step they took was to try in vitro fertilization, or IVF. This involves fertilizing eggs with sperm in a laboratory dish, then transferring the embryo into the woman's uterus. It can cost $15,000 to $20,000 each try.

"At first, Greg says, they thought about traveling overseas for more affordable treatments, but travel costs would have gobbled up any savings. So, they went online instead, to the crowdfunding site GiveForward. "

Removing financial disincentives to kidney donation in the U.S.

A forthcoming article in the American Journal of Transplantation, by authors who are firmly opposed to creating incentives for donation, show increasing acceptance of reimbursing donor expenses...but there is as yet too little action towards making that happen.


Providing coverage for the unique life-long health care needs of living kidney donors within the framework of financial neutrality

John S. Gill, Francis Delmonico, Scott Klarenbach and Alexander Morgan Capron

Accepted manuscript online: 26 NOV 2016

Abstract

Organ donation should neither enrich nor impose financial burdens on donors. We describe the scope of health care required for all living kidney donors that reflects contemporary understanding of long-term donor health outcomes, propose an approach to identify donor health conditions which should be covered within the framework of financial neutrality, and propose strategies to pay for this care. Despite the Affordable Care Act in the United States, donors continue to have inadequate coverage for important health conditions that are either donation related or may compromise post-donation kidney function. Amendment of Medicare regulations is needed to clarify that surveillance and treatment of conditions that may compromise post-donation kidney function following donor nephrectomy will be covered without expense to the donor. In other countries lacking health insurance for all residents, sufficient data exist to allow creation of a compensation fund or donor insurance policies to ensure appropriate care. Providing coverage for donation-related sequelae as well as care to preserve post-donation kidney function ensures protection against the financial burdens of health care encountered by donors throughout their lifetime. Providing coverage for this care should thus be cost-effective even without considering the health care cost savings that occur in living donor transplant recipients. T 

Conclusion

It is now widely accepted that to remove economic barriers to donation and achieve a fair and successful program of living organ donation, the gift of an organ must be “financially neutral” for the donor. Financial neutrality requires that donors be protected against health care costs arising from post-surgical events, and medical complications that manifest in the weeks or months after the donation, as well as the long-term care of conditions that may compromise residual kidney function.

Strategies to provide for the particular lifelong health care needs of living donors will vary among countries. Limiting coverage to the costs arising from the donation and its potential sequelae including loss of post donation kidney function will avoid creating an inducement to donate—and the consequent violation of financial neutrality—that would arise were countries to offer living donors comprehensive medical insurance as a means of covering donors’ future health-care costs.

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and here's an earlier related paper...

Am J Transplant. 2015 May;15(5):1187-91. doi: 10.1111/ajt.13232. Epub 2015 Mar 31.

Living and deceased organ donation should be financially neutral acts.

Delmonico FL¹, Martin D, Domínguez-Gil B, Muller E, Jha V, Levin A, Danovitch GM, Capron AM

Abstract

The supply of organs—particularly kidneys—donated by living and deceased donors falls short of the number of patients added annually to transplant waiting lists in the United States. To remedy this problem, a number of prominent physicians, ethicists, economists and others have mounted a campaign to suspend the prohibitions in the National Organ Transplant Act of 1984 (NOTA) on the buying and selling of organs. The argument that providing financial benefits would incentivize enough people to part with a kidney (or a portion of a liver) to clear the waiting lists is flawed. This commentary marshals arguments against the claim that the shortage of donor organs would best be overcome by providing financial incentives for donation. We can increase the number of organs available for transplantation by removing all financial disincentives that deter unpaid living or deceased kidney donation. These disincentives include a range of burdens, such as the costs of travel and lodging for medical evaluation and surgery, lost wages, and the expense of dependent care during the period of organ removal and recuperation. Organ donation should remain an act that is financially neutral for donors, neither imposing financial burdens nor enriching them monetarily.

The politics (and incentives) of liver transplants

From the LA Times: California has long wait lists for liver transplants, but not for the reasons you think

"About 7,000 people get a liver transplant each year in the United States, while 17,000 remain on waiting lists at transplant centers. Who should get a lifesaving transplant has always been a complex calculation. But it has blown up into a vicious political struggle that played out most recently at a meeting of the organization governing the nation’s transplant network.

"The benefits of liver transplants are astounding. Patients just weeks from death can have their lives extended significantly, even indefinitely. Given the limited number of donor livers, in 2000 Congress established what’s called “the Final Rule” to guide the medical community in how to allocate them fairly. The Final Rule compels the transplant community to allocate donor organs based on best medical judgment, best use of the organs and avoidance of futile transplants. It also notes that a patient’s chance of getting a transplant should not be affected by where he or she lives.

"Balancing these various guidelines has always been tricky. But what has emerged — and is now the point of contention — is a marked geographic disparity in how sick a patient must be before rising to the top of a transplant list. For example, waiting lists at California transplant centers are significantly longer (and therefore patients in California get a lot sicker before possibly receiving transplants) compared with waiting lists in Oregon. That’s unfair to the Californians who need liver transplants, right?

"Acting on this assumption, the national board of the Organ Procurement and Transplantation Network / United Network for Organ Sharing, or OPTN/UNOS, proposed new boundaries for the nation’s transplant regions. The aim was to have regions with shorter, less-sick waiting lists share the limited supply of donor livers with regions that have longer, more-sick waiting lists. The new map was recently offered for public comment and a regional advisory vote.

"Eight of the 11 regions came out against it — because longer waitlists aren’t necessarily a sign of greater need.

The divide is deep. Antagonists have split into camps (“Liver Alliance” versus “Coalition for Organ Distribution Equity”), hired lobbyists and collected their congressional representatives. Given the uproar, it was not surprising that the OPTN/UNOS board of directors declined to vote on the controversial proposal at its national meeting in St. Louis last week. Nevertheleess, there’s a feeling of urgency that something must be done, so it’s entirely possible the board will soon enact the redistribution proposal — perhaps with minor modifications — despite present objections.
...
"Transplant waiting lists also get distorted by intense competition in populous regions where there are more liver transplant centers — a largely ignored issue. With money and prestige at stake, centers are motivated to perform more liver transplants. The simplest way to accomplish that is to put very ill patients on the transplant list, because when a donor organ becomes available, the center with the sickest listed patient in that region gets the organ.

Unfortunately, this encourages centers to list sicker patients over those who have the best chance of long, high-quality lives post-transplant.
...
"Rates of organ donation, by the way, do not explain the wait-list problem: California has some of the highest donation rates in the country, while New York persistently ranks at the bottom. Everyone agrees on the need to increase donations — but just redistributing livers will not significantly change the number of transplants or lives saved.

"Still, the disparity between the wait lists causes endless teeth-grinding in the transplant community.

"There is no question that wait lists are abhorrently long in some places, but OPTN/UNOS’ redistribution proposal misses the larger point: What is it about our transplant system that has created this situation? How can we make changes to keep the wait lists at more reasonable levels?

"Matters of healthcare access, while important, are beyond the control of OPTN/UNOS and the transplant community. Within grasp, however, is a simple solution: Lower the number of patients on transplant lists. Such a move would not affect the number of transplants (every available liver would still be transplanted), but it would reduce the delay and degree of illness for those on the wait lists. This is, of course, simple to say, but difficult to implement given how our current system incentivizes transplant centers to get as many patients on their lists as possible.

"To create a fairer balance between the haves and have-nots, though, both factions in the liver debate need to understand (and agree on) who the haves and have-nots actually are. Without consensus on that, we risk missing the big picture: increasing the health, happiness and well-being of more people with liver disease."

Dr. Willscott E. Naugler is an associate professor and medical director of liver transplantation at Oregon Health & Science University in Portland. He also serves as the Region 6 (Pacific Northwest) regional representative to the UNOS Liver and Intestine Committee."

Genos seeks to make a market for personal genetic (whole exome) information

Genos is a new company that seeks to make a market for personal genetic information--it wants to both sell sequencing services to individuals, and then serve as a broker between the individuals who will still own their own data, and research projects that wish to use those data.

Here's an article in WIRED:

Genos Will Sequence Your Genes—And Help You Sell Them to Science

"The latest contender is Genos, a genetic sequencing startup that is unveiling its whole exome-sequencing service today. The hot, shiny object of the industry, this type of next-generation sequencing offers a complete profile of all the expressed genes (the ones that code for proteins) in your genome. While a growing number of targeted genetic testing kits are currently on the market (Color, Myriad, and 23andMe, to name a few), whole exome sequencing produces 50 to 100 times more data.
...
"In a first for the personal genomics movement, the company is creating a research pipeline with academic and commercial partners, and paying customers to donate their data. The incentives range between $50 and $200 per project; the first four include a vaccine for breast cancer, a clinical trial for treating lymphoma, and research into prion diseases and common neurological disorders."
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A market for information will have some interesting design issues, and a market for genetic information will have to navigate issues of repugnance as well. I'm on their advisory board.

Here's a press release.

Marijuana becomes legal in Massachusetts today

Here's a story that ran yesterday in the Boston Globe:
It’s official: Marijuana legal at midnight in Massachusetts

"Marijuana will be legal for possession, use, and home-growing Thursday for adults 21 and over.
...
"The initiative passed last month with 1.8 million people voting for the measure, despite the opposition of top politicians, the Catholic Church, doctors and business groups, and an array of other civic leaders. About 1.5 million people voted against it.
...
"For legalization advocates, the strike of midnight Thursday will represent the culmination of a long twilight struggle that was met with dismissal for decades, but increasing acceptance in recent years. Massachusetts voters decriminalized the drug in 2008, replacing the criminal penalties for possession of one ounce or less with a new system of civil penalties. And, in 2012, voters approved a ballot question legalizing marijuana for medical use.
...
"The law allows adults to grow up to six plants per person, with a maximum of 12 per household. It mandates the state treasurer appoint a three-person Cannabis Control Commission to regulate the new industry. And it sets a January 2018 timeframe for when retail pot shops can open.

"But the framework is likely to be tinkered with by politicians who believe it does not sufficiently protect public health and safety. Top leaders have discussed the prospect of delaying the opening of stores to give policymakers more time.

"For law enforcement the journey ahead may be the most rocky, especially in the next year.

"They will be forced to navigate a legal gray zone in which marijuana is legal for purchase, possession, and use, but the drug remains illegal to sell. (Sales are legal only through the regulated market, which won’t start until 2018.)"

Non-market surrogacy (the urge to have children is strong...)

Here's a moving story from England (where  paid surrogacy is illegal) about within-family surrogacy that also involves a number of other reproductive technologies that have sometimes met with opposition in some quarters:
Woman gives birth to own grandson as surrogate for her cancer survivor daughter

 "Ms Jenkins said: "They managed to take 21 eggs before I started chemo but only 10 survived. They were made into embryos and grown for two weeks, then frozen.

"Then in May this year we had an embryo defrosted and implanted into my mother's womb..."

Tom Schelling (1921-2016)

Tom Schelling has passed away. Here's an obit in the Washington Post:
Thomas Schelling has died. His ideas shaped the Cold War and the world.

His 1960 book The Strategy of Conflict is one of the first books I read about game theory. It was both an introduction to game theory, and a critique of some of its conventional formulations. I still sometimes teach some of the experiments he wrote about there.

He shared the 2005 Nobel Prize in Economics with Bob Aumann

John Dickerson speaks on Kidney Exchange in DC

If you're in DC today...

Swapping Kidneys: Better Matching Market Design via Optimization

 Tuesday, December 13, 2016

• 6:30 PM
• GWU, Funger Hall, Room 108

  2201 G St. NW, Washington, DC (map)
• For our last Data Science DC Meetup of 2016, we are excited to have John Dickerson join us to talk about Matching Market Design -- where techniques from computer science and operations research are combined with massive data to optimize kidney exchange between donors and patients. John is an Assistant Professor in the Department of Computer Science at the University of Maryland working at the intersection of computer science, AI, and economics, with a focus on solving practical problems using stochastic optimization and machine learning.

Black market for babies in Malaysia

Al Jazeera files this report: BABIES FOR SALE:  Malaysia's underground baby trade

"The babies offered for sale come from a variety of women. Some are poor migrant workers who, by law, are not allowed to have children in the country. Others come from Malaysian women, including some who are forced to give up their babies to avoid the stigma associated with having a child out of wedlock.

"The buyers are often childless couples desperate to start a family and frustrated with the country's convoluted adoption procedures. But activists say some babies are bought for more sinister purposes, sometimes by syndicates who groom children for paedophiles.
...
"During our investigation into Malaysia's baby trade, it was easy to find a woman who wanted to sell her unborn child.

One Filipino who was six months pregnant offered her baby boy for $2,000, plus the cost of her monthly check-ups and the baby's delivery fee.

"The baby is healthy and actually the baby is starting to move now," the expectant mother told our undercover reporters who were posing as a couple who were unable to have children.

The woman said she had been working in Kuala Lumpur, but her work visa had expired. Migrant workers are not allowed to bear children in Malaysia, and her child would be stateless if born in the country."

Festival of Economics in Trento, June 1-4, on health inequality

The initial announcements for the 12th Festival of Economics in Trento in June 2017 have appeared: the theme will be health inequality.
I expect to speak about kidney exchange, and in particular global kidney exchange between rich and poor countries.

A Trento dall’1 al 4 giugno 
Il Festival dell’Economia 2017 dedicato al tema: “La salute disuguale”

Festival economia 2017: protagonista 'La salute disuguale'
Boeri, tra i partecipanti Nobel Roth e epidemiologo Marmot

Repugnant money in England

I've written a lot about repugnance and money, but never quite like this. Here's the Telegraph story on some new banknotes:
New £5 notes contain animal fat, says Bank of England, drawing anger from vegans and vegetarians

"Vegans and vegetarians have voiced outrage after it emerged the new £5 notes contain tallow, a substance made from animal fat...
...
"More than 1,700 people so far have signed a petitiondemanding that the substance is no longer used in the production of the currency. 

"The new £5 notes contain animal fat in the form of tallow. This is unacceptable to millions of vegans & vegetarians in the UK. We demand that you cease to use animal products in the production of currency that we have to use," the petition read."

Dutch hospital director becomes anonymous kidney donor

Joris van de Klundert points me to the following story:
Voorzitter AMC geeft het goede voorbeeld als anonieme donor--
Ziekenhuisbestuurder schenkt een nier aan een onbekende
(Google translate: "Chairman AMC sets a good example as anonymous donor--
Hospital Director donates a kidney to a stranger")

"Levi (52) was operated on in his own hospital. When that happened, he would not say, because the recipient could then figure out his identity. This is undesirable, for an anonymous donation in order to protect the privacy.

"He tells his story because he wants to encourage others to think about undertaking organ donation.
...
"Thanks to a donor kidney dialysis patients do not have more weekly. Dialysis takes time, has serious side effects and worsens the health of patients.

"Levi is one of the seven people who have donated a kidney in the hospital this year an unknown. The Dutch Transplant Foundation (NTS) is no national records of the numbers of so-called altruistic donations, but thinks that it is a few dozen per year."

Opposition to kidney sales in Iran

Afshin Nikzad points me to the following story in Farsi, and provides the translation below. He writes:

http://donya-e-eqtesad.com/SiteKhan/1136026/

"I edit/copy parts of the article from google translate (since it didn't give a great translation) : 

The 78 years old residing in America in an interview with US media said he had been in America for a kidney transplant and doctors had told him he should stay on the waiting list for a kidney transplant from brain death or that of one of his two children. All catch. But he found a third way through his Iranian birth certificate: buying a kidney in Iran. In his interview he talked about the youth in Iran who from the poverty and desperation were lined up to speak to him for selling their kidney.

Doctor, "Ali Husseini,” the head of the Transplantation Society of the Middle East in response to the letter, said: "Buying and selling kidney with strangers is dirty and inhumane and is banned even in countries like India and Pakistan" He also said “among all the thousands seller in the country there is not a single a rich person, all were poor and sold the kidney from poverty and desperation; undoubtedly they  have not donated their kidney.”

Dr. Mohammad Reza Ganji, head of the Iranian Society of Nephrology said “… In the past two years  63% of the transplants have been from brain-dead (that is two thousand and six hundred transplants), and this is statistically significant in the world."

Family consent for deceased organ donation in Canada

The National Post has the story:
One in five willing organ donors in Ontario have their wishes vetoed by family — and doctors don’t argue

"Legislation in most provinces and territories outlines legal authority for organ procurement from someone who has died. Written consent, such as an organ donor card or an online registration form, is legally binding. Family members can’t revoke that consent in most Canadian jurisdictions (the law is less clear in the North West Territories) — their refusal is legally meaningless.

"Despite the legal authority to do so, every provincial donation organization in Canada has a policy that the wishes of families will be followed (except Manitoba, where the wording is vague). Alberta legislation clearly prohibits seeking family consent when donor consent was previously provided and yet an Alberta Health Services directive states “your next of kin will be asked by the donation team to sign a consent form.”

"With more than 4,000 Canadians waiting for a lifesaving transplant, the gap between the law and what actually happens is glaring.

“People who register want donation to be part of their legacy,” says Linda Wright, the former director of bioethics of the University Health Network in Toronto, where more organ transplants are performed than anywhere else in Canada.

“As a living person you want to know your wishes will be respected,” she says, but health-care providers “don’t want to further traumatize families” often shocked and devastated over the sudden loss of a loved one.

"To date, no physician in Canada has ever overridden the wishes of the family in favour of the legally binding consent of the potential donor."

Conference on Economic Design: York, United Kingdom, June 14-16, 2017

2017 Conference on Economic Design: York, United Kingdom, June 14-16, 2017

The tenth bi-annual Conference on Economic Design will be held at the University of York, United Kingdom, on three full days June 14-16 (Wed--Fri), 2017. It will be organised by the Economics Department of the University of York and the Centre for Mechanism and Institution Design. The conference welcomes paper submissions from many different fields such as economics, business, finance, politics, computer science, operations research, law, history relevant to mechanism or institution design in a broad sense, regardless of whether contributions are theoretical, empirical, experimental, historical or practical. Subjects include but are not limited to auctions, matching, school choice, college admission, organ exchange, decentralised markets, random market mechanisms, voting, social choice, taxation, tax reform, coalition formation, price formation, ranking and scoring, measurements of power and influence, contest, fair division, contract, bargaining, negotiation, market design implementation, pricing on electricity, pricing on public utilities, pricing on cloud computing services, online allocation mechanisms, online auctions, market design experiments, public goods experiments, behavioural mechanism design, information and incentive, digital sport market for labour, market design in transportation sector, institution and organisation, health care, health policy, health insurance, pension scheme, fiscal policy, monetary policy, growth and development, performance evaluation, arbitration, patent design, governance, etc. York is a beautiful historical city with a rich heritage and a wealth of attractions being one of the most popular tourist destinations in the UK. We would like to advise you to make a hotel reservation as soon as possible if you wish to attend the conference, in order to avoid a shortage of affordable accommodation. The Keynote Speakers are: Sanjeev Goyal (Cambridge) Parag Pathak (MIT) Philip Reny (Chicago) Important Dates: Paper Submission Opens: 20-Nov-2016 Paper Submission Deadline: 16-Feb-2017 Notice of Accepted Papers : 1-Mar-2017 until 6-Apr-2017 Registration Opens: 10-Mar-2017 Early Registration Deadline: 20-Apr-2017 Registration Deadline: 20-May-2017 Conference Fees: Regular participants: Until 20-Apr-2017: £330 (GBP), after 20-Apr-2017: £380 (GBP) Student participants: Until 20-Apr-2017: £190 (GBP), after 20-Apr-2017: £230 (GBP) (Fees include a gala dinner, 3 lunches, drinks, a two-year membership of the Society for Economic Design and a subscription to the Review of Economic Design.) Paper Submission: We start to accept paper submissions from 20th Noverber 2016 until 16th February 2017. Each individual is allowed for only one paper submission. Papers should be submitted in PDF with a cover letter to CED2017york@gmail.com. If the author is a student, it is advised to declare it.