International statistics on plasma donation show that it is quite safe

 Peter Jaworski collects the statistics from Europe and North America:

Plasma donation is safe
And commercial plasma donation is not less safe than non-commercial donations
Peter Jaworski
Mar 16, 2026 

"Source plasma donation (also called “plasmapheresis”) is inordinately safe (so is whole blood donation). And the best publicly-available donation safety data give us no reason to think that commercial plasma collection is less safe than non-commercial plasma collection.

" That claim may be surprising in light of the recent heartbreaking deaths reported after plasma donations in Winnipeg. These tragedies have raised questions about the safety of plasma donation in general, with some critics suggesting that commercial plasma donation is inherently less safe than non-commercial plasma donation.

"The evidence for the claim that plasmapheresis, including commercial plasmapheresis, is safe can be found in countries with the largest plasmapheresis programs, which publish annual reports on serious donor adverse events. Some of these countries have exclusively non-commercial plasma collection, while others have predominantly commercial systems. "