Dr. Steve Woodle, one of the pioneers of kidney exchange, is being honored in Cincinnati. You can read of his many distinctions below, but here's a striking one: he is the "the first liver transplant recipient to perform a liver transplant."
2026 Daniel Drake Medals The University of Cincinnati College of Medicine’s highest honor
E. Steve Woodle, MD

E. Steve Woodle, MD
Woodle, professor of surgery and the William A. Altemeier endowed chair in surgery at the College of Medicine, is a multiorgan transplant surgeon and transplant immunologist who has spent more than four decades advancing the understanding of organ rejection and pioneering immunosuppressive therapies that have reshaped transplantation. Earlier in his career at the University of Chicago, he performed a liver transplant on a 10-day-old infant, setting a Guinness World Record for the youngest liver transplant recipient. He joined the College of Medicine in 1999 and directed the Division of Transplantation for nearly two decades, building an internationally recognized program of clinical and research excellence. In 2001, he performed Ohio’s first allogeneic islet transplant for type 1 diabetes. After undergoing his own liver transplant in 2003, Woodle returned to the operating room and became the first liver transplant recipient to perform a liver transplant.
Woodle has helped originate several therapeutic approaches now considered standard in transplantation. As a fellow, he conceived the genetic re-engineering of OKT3, the first FDA-approved monoclonal antibody — work later developed into teplizumab (Tzield), which the FDA approved in 2022 as the first immunomodulatory therapy for type 1 diabetes. He was the first investigator to introduce plasma cell-targeted therapy for a non-malignant human disease, using proteasome inhibitors to treat antibody-mediated rejection in kidney transplant recipients. He also pioneered corticosteroid-free immunosuppression, including the field’s landmark double-blind, placebo-controlled trial of early corticosteroid withdrawal. He helped conceive and establish clinical kidney exchange for incompatible living-donor pairs, publishing the field’s first peer-reviewed description in the New England Journal of Medicine in 1997. Kidney exchange now accounts for roughly one in five living-donor kidney transplants in the U.S.
His scholarship includes more than 400 scientific publications cited more than 22,000 times, and he has delivered more than 700 invited lectures and mentored generations of transplant surgeons, physicians and pharmacists. In 2025, he received the American Society of Transplantation’s Senior Achievement Award in Clinical Transplantation and was named an Ashbel Smith Distinguished Alumnus by the University of Texas Medical Branch, where he earned his medical degree.
Featured photo at top: Daniel Drake Medal. Photo/University of Cincinnati.