Showing posts sorted by date for query sperm. Sort by relevance Show all posts
Showing posts sorted by date for query sperm. Sort by relevance Show all posts

Monday, October 19, 2026

Moral Economics reviewed in American Journal of Transplantation

 I wonder if this is the first time an economics book has been reviewed in the American Journal of Transplantation.

Poetic justice: A review of moral economics by Alvin E. Roth
Michael A. Rees

 "Alvin E. Roth describes poetic justice as the Virginia state flag flying at half-mast in 2020 in honor of Bernie Cohen, who argued the US Supreme Court case Loving v. Virginia that made interracial marriage legal. Turns out Mildred and Richard Loving were convicted of interracial marriage in 1967, arrested by police at 2 AM at home in their bed, and sentenced to 1 year in prison but suspended on the condition that they leave Virginia for 25 years. Reading what the Virginia Court of Appeals judge wrote, side by side with what the US Supreme Court wrote, is, by itself, worth the price of the book.
 

"Those of us in the field of transplantation have felt—and will continue to feel—the impact of repugnance. In moral economics, Alvin E. Roth takes us on a grand tour of how repugnance shapes transactions across a wide spectrum of human activities. Take uterus transplantation, pioneered in Sweden, a country where repugnance to surrogacy has made it illegal. You can transplant a uterus into a woman with infertility in Sweden, but do not you dare use a surrogate’s uterus in her own body to help you achieve a baby! Alvin E. Roth defines repugnance as a morally contested market that some people would like to participate in, but others think should be outlawed. He goes on to call a transaction repugnant if “all parties to the transaction want to engage in it, and others think they shouldn’t be allowed to for moral or religious reasons, even though those others can’t detect that the transaction has taken place unless someone tells them.”1 I found it fascinating to walk through all the ways in which repugnance has shaped the world in which we live.
 

"The book starts with a clear example of a transaction that many people want to engage in: sex. Of course, I knew about the repugnance surrounding prostitution and pornography, but could hardly believe the stories of how far people go on either side of a repugnant transaction. I found my own views challenged by what I thought was right, especially when considering the outcome I desired from the controversy being described. It was interesting to have these stories told by the “Father of Market Design” and to think about sexual desire as a contested marketplace with good and bad outcomes that could be influenced by better market design.
 

"It is not the first time I have been surprised to think about a human desire for something like love or health as a transaction that economists could study. I first met Alvin E. Roth in about 2004 when he thought he could help us transplant professionals do a better job with kidney exchange. I made the mistake of thinking that economists only worried about money, albeit at both the microlevel and macrolevel. This book makes clear that if we want to have the desired outcome of helping as many people as possible through organ transplantation, we are going to have to think like market designers and overcome repugnance to innovation. Remember Richard Lower in 1968 being threatened with criminal charges for “wrongful death” for removing a donor heart prior to the establishment of brain death criteria?
 

"My favorite chapter was about reproduction. You would not believe all the interesting twists and turns that have happened as artificial reproductive technology has blossomed, and some people wanted to have babies using it, whereas others were morally aghast at their desire, working hard to stop them. It was interesting to see different sides of contraception, abortion, in vitro fertilization, egg and sperm donation, paternity, maternity, parenthood, and surrogacy. But Alvin E. Roth has such a nice way of distilling complicated concepts, such as this quote: “Some critics have said that looking for an egg donor who attends Harvard, for example, reeks of eugenics. In response to that, Professor Kim Krawiec, perhaps the leading legal scholar of “taboo trades,” gave a very cogent response: “Fertile people have been screening for beauty and intelligence for years and years. It’s called dating.”2
 

"If transplantation attracted you as a field in part because of the ethical challenges encountered when considering organ donors and recipients, Moral Economics provides a narrated guide through thorny issues. Near the end of the book, we find perhaps the best call to action for those of us who want to solve problems. The Persian poet Rumi invites us to navigate repugnance: “Out beyond ideas of wrongdoing and rightdoing, there is a field. I’ll meet you there.”3
 
1. Roth, A.E.
Moral Economics: From Prostitution to Organ Sales, What Controversial Transactions Reveal About How Markets Work. Hachette UK; 2026
2026

2. Jones, A. Putting a Price on a Human Egg.”
Wall Street Journal. July 26, 2015;
Accessed XXX www.wsj.com/articles/putting-a-price-on-a-human-egg-1437952456


3.Rumi, “Out Beyond Ideas of Wrongdoing and Rightdoing.” Poetry Society of America. 

Thursday, September 10, 2026

Surrogacy (on each side of the Atlantic)

 Crossing the Atlantic today, to return home from Paris, this story in The Atlantic seems apropos:

Mothers for Sale.  Most of Europe bans commercial surrogacy. The United Nations likens it to slavery. But in the United States, business is booming.  By Helen Lewis

"Since the legalization of same-sex marriage, male couples have become the big growth market for American surrogacy, but the practice is booming among aspiring parents—married or single, straight or gay—who can afford the cost of hiring someone else to carry their child. In 2024, 11,821 embryos were transferred to surrogates in American clinics associated with the Society for Assisted Reproductive Technology, up from 8,461 three years earlier, and the United Nations estimates that the global worth of the industry is almost $15 billion. Most surrogacy in America today is commercial, meaning that the carrier is paid, and gestational, meaning that the carrier has no genetic relationship to the child.

...

" many liberal Americans are surprised to discover that their country is an outlier in its enthusiasm for commercial surrogacy. In Britain, where I live, a ban on the practice enjoys substantial support among feminists, who worry about the power differential between paid surrogates and wealthy would-be parents. (Altruistic surrogacy, in which the surrogate carries a baby solely out of generosity, is less controversial and is permitted.) A recent UN report went even further, declaring that commercial surrogacy “constitutes the sale of children, which is a crime,” and that “surrogacy arrangements can amount to or resemble slavery.” 

...

"Because so much can go wrong, every country in the European Union has banned commercial surrogacy. France’s centrist liberal president, Emmanuel Macron, has described the practice as “not compatible with the dignity of women.” Italy’s right-wing populist leader, Giorgia Meloni, has enacted one of the strictest anti-surrogacy frameworks in the world. Not only is domestic surrogacy banned, but any Italian citizen who brings home a baby born to an overseas surrogate risks jail and a fine of up to 1 million euros. Many other developed countries have either tightly restricted surrogacy or chosen, as Britain and Canada have, to allow only the altruistic version. Israel allows surrogacy but imposes a raft of conditions: The commissioning parents must not have more than two children already, must not have serious criminal convictions, and must be of the same religion as the surrogate.

"In general, Europeans think of Americans’ enthusiasm for paid surrogacy the way we regard their fondness for guns and capital punishment: inexplicable. The piquant difference, however, is that surrogacy is a cause of the American left rather than the right. Red states tend to have tighter limits on surrogacy. Louisiana, for example, restricts surrogacy to married heterosexual couples using their own sperm and eggs. By contrast, when New York legalized commercial surrogacy in 2020, LGBTQ activists hailed it as a triumph for “fertility equality.”

The debate cuts across political traditions and defies easy categorization. When surrogacy goes well, the result is a happy family that would not otherwise have existed. When it goes wrong, however, it can do so in unpredictable and emotionally crushing ways. At its core, the ethical question is this: How much physical and emotional risk should individuals be allowed to take on in the name of a commercial transaction? 

...

"America also stands virtually alone as a rich country that permits incoming surrogacy tourism from elsewhere. Many of these international intended parents are from China, where surrogacy is banned and where, until recently, family size was limited by the one-child policy. These customers have exacting standards. 

...

"Look abroad, though, and it’s a different story. Some agencies offer “guaranteed baby” packages for as little as $50,000. Surrogacy destinations pop up anywhere the local laws are lax, such as Northern Cyprus, a territory that exists in a legal limbo and is recognized only by Turkey. (The problem is that babies born there can end up stateless.) For parents from Russia, nearby Georgia is a similar no-questions-asked destination.

"India used to be the most favored low-cost destination, but in 2015, Prime Minister Narendra Modi, citing fears of exploitation, banned commercial surrogacy for foreigners. Ukraine’s appeal as a surrogacy destination has diminished since Russia’s invasion in 2022, although the leading agency there, BioTexCom, told me that the company is still handing off one baby born via surrogacy every day on average, at a cost of about $60,000. A representative of the agency initially told me that it was planning to open a clinic in Kazakhstan, to cater to the growing Asian market. In July, however, that country abruptly banned foreign surrogacy amid concerns about exploitation. "
 



 

Monday, April 13, 2026

Complex tragedy in a headline: Israeli Court Lets Parents of Gaza Hostage Killed by IDF Fire to Use Son's Sperm for IVF

 Rarely does a headline capture so much of a complicated tragedy.  Read it at least twice.

From Haaretz: 

Israeli Court Lets Parents of Gaza Hostage Killed by IDF Fire to Use Son's Sperm for IVF 

"An Israeli family court has allowed the parents of Yotam Haim, who was mistakenly killed by Israeli troops after escaping Hamas captivity, to use his sperm posthumously for in vitro fertilization, citing his presumed wish to have children even after his death. "

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This is a story that also involves the modern technology that can be brought to bear on human reproduction, including not only sperm donation and IVF, but also perhaps egg donation and surrogacy. 

Saturday, May 31, 2025

Children adopted from China can now find birth-family connections via DNA sites

 Like children conceived with the help of anonymous sperm donors, adopted children can use DNA websites to search for family members.  For children adopted from China during the one-child policy period, that can mean finding siblings and even parents who may have put them up for adoption under duress.

The New Yorker has the story:

The Chinese Adoptees Who Were Stolen. As thousands of Chinese families take DNA tests, the results are upending what adoptees abroad thought they knew about their origins.
By Barbara Demick   May 23, 2025

"Back when China started allowing foreign adoptions, in the early nineties, there was no expectation that adoptees would ever connect with their birth families. The babies, mostly girls, were said to have been picked up at train stations, markets, and roadsides, where they had been abandoned by families fearful of the ruthlessly enforced one-child policy. They had no identification. Even the orphanages didn’t know who they were. And China, with its staggeringly large population—more than one billion—was so far away from the adoptive parents. An adoptee finding her birth family seemed no more likely than locating a particular grain of sand.

"Those assumptions have been upended in recent years. Like it or not, and many do not, technology has compressed this vast world into an interconnected village. Adoptees who could only fantasize about their birth families are now identifying them through DNA testing and chatting with them online. Even more unexpected, Chinese birth parents and, sometimes, adult siblings are seeking out and finding their lost kin who were adopted abroad."

Saturday, April 26, 2025

Prolific sperm donation and incest risk in the Netherlands

 The Guardian has the story:

‘Medical calamity’: dozens of Dutch sperm donors fathered at least 25 children.  Discovery that clinics have been breaking rules raises genetic risks in such a small, densely populated country  by Jon Henley 

"At least 85 sperm donors in the Netherlands have fathered 25 or more children, the national gynaecology and obstetrics organisation has said, after a new registration system showed fertility clinics have been breaking existing rules on sperm donation for decades.

"The NVOG said on Monday that some clinics had deliberately used sperm batches more than 25 times, exchanged sperm without the necessary paperwork or donors’ knowledge, and allowed the same donors to donate sperm at multiple clinics.

“The number of so-called ‘mass donors’ should be zero,” gynaecologist Marieke Schoonenberg told the TV show Nieuwsuur. “On behalf of the whole profession, we wish to apologise. We didn’t do things as they should have been done.”

"A law aimed at reducing the risk of involuntary incest and inbreeding should have barred donors from fathering more than 25 children in the Netherlands since 1992, but proved difficult to enforce because of strict privacy laws.

"The limit was lowered to 12 in 2018, but the means to enforce it – a national register of donors and mothers with a code system ensuring sperm from the same donor cannot be used in more than 12 conceptions – came into force, retroactively, only in April.

“As a result, we now know, for the first time, the exact number of children per donor,” Schoonenberg said. Since 2004, when donors’ right to anonymity was lifted, the data showed there had been at least 85 “mass donors” (defined as at least 25 conceptions) in the Netherlands, she said.

"Most were biological father to between 26 and 40 children, Schoonenberg said, although several had between 50 and 75. Among them were at least 10 fertility doctors, including Jan Karbaat, who illegally fathered at least 81 children at his clinic.

"The most prolific donor was Jonathan Jacob Meijer, the subject of the Netflix documentary The Man with 1,000 Kids, who is known to have fathered at least 550 children worldwide. More than 100 of Meijer’s children were conceived in Dutch clinics.

"Ties van der Meer, of Stichting Donorkind, a foundation that helps children trace their donor fathers, said the findings were a “medical calamity”. The data meant there were probably at least 3,000 children in the Netherlands with 25 or more half-brothers and sisters, he said."



Monday, January 20, 2025

Emerging Technologies to Stop Biological Time: The Ethics of Refrigeration

 Here's a special issue of the Journal of Law, Medicine & Ethics, exploring the promise and peril of refrigeration (as applied e.g. to organ transplantation). 

Here's how the introduction to the issue begins:

" Human beings depend on biological materials for survival — everything from food to medical interventions such as organ transplantation, to the environments in which we live. So it is no surprise that techniques to avoid the deterioration of biological materials have been used since ancient times.Reference Knorr and Augustin1 Cooling is one of the oldest techniques. Indeed, most of us now live with a cooling machine — a refrigerator — in our kitchens. But the function of those machines is primarily to retard the spoilage of materials that are already in the process of disintegrating: fruit that has already been harvested, meat from beef and chickens already slaughtered, and milk already derived from cows.

Beginning in the mid-20th century, scientists began to develop techniques for cryopreservation with more ambitious goals in mind. Instead of merely slowing the deterioration of biological materials, techniques could be developed to preserve living materials for prolonged periods of time and then allow their revival and use at a future time and place. An early application was cryopreservation of sperm (both human and animal), allowing sperm banking and later use.Reference Walters, Pacey and Tomlinson2 Yet conventional cryopreservation had its limits. Prolonged preservation of solid organs for transplantation was among the applications that proved elusive."

Emerging Technologies to Stop Biological Time: The Ethical, Legal & Policy Challenges of Advanced Biopreservation   Volume 52 - Issue 3 - Fall 2024
Latest issue of Journal of Law, Medicine & Ethics 

Introduction

Symposium Articles

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Earlier post (on what turns out to have been a seminal paper: "Since Giwa and colleagues reviewed the emerging field of biopreservation in biomedicine in 2017, progress has been swift."):

Monday, June 12, 2017 Organ preservation could bring big changes to transplantation