Wednesday, December 27, 2023
Medical aid in dying considered in Britain, and evolving in Canada
Wednesday, October 25, 2023
Why living kidney donors in England should be financially compensated
Here's an article suggesting why England should pilot a program to compensate kidney donors. Perhaps the argument is generalizable to other countries as well...
Rodger, Daniel, and BonnieVenter, A fair exchange: why living kidney donors in England should be financially compensated. Medicine, Health Care and Philosophy (2023). https://doi.org/10.1007/s11019-023-10171-x
Abstract: Every year, hundreds of patients in England die whilst waiting for a kidney transplant, and this is evidence that the current system of altruistic-based donation is not sufficient to address the shortage of kidneys available for transplant. To address this problem, we propose a monopsony system whereby kidney donors can opt-in to receive financial compensation, whilst still preserving the right of individuals to donate without receiving any compensation. A monopsony system describes a market structure where there is only one ‘buyer’—in this case the National Health Service. By doing so, several hundred lives could be saved each year in England, wait times for a kidney transplant could be significantly reduced, and it would lessen the burden on dialysis services. Furthermore, compensation would help alleviate the common disincentives to living kidney donation, such as its potential associated health and psychological costs, and it would also help to increase awareness of living kidney donation. The proposed system would also result in significant cost savings that could then be redirected towards preventing kidney disease and reducing health disparities. While concerns about exploitation, coercion, and the ‘crowding out’ of altruistic donors exist, we believe that careful implementation can mitigate these issues. Therefore, we recommend piloting financial compensation for living kidney donors at a transplant centre in England."
They set the stage in their Introduction:
"In 2019, the Human Tissue Act 2004 (HT Act) was amended to allow England to adopt an opt-out system of organ donation, which was subsequently passed as The Organ Donation (Deemed Consent) Act 2019 and implemented in May 2020. This amendment aims to change the way donor consent is given for transplantable organs and tissues. Its intention is to increase the number of organs available for transplantation to save lives and improve the quality of life of those on the wait list. It was estimated by the United Kingdom (UK) Government that this amendment would save 700 lives per year (Dyer 2019). Despite these intentions, this amendment is unlikely to make a significant difference to the number of available organs.
"Currently, there is no definitive evidence to suggest that merely adopting an opt-out system will increase the pool of available organs (Etheredge 2021). Nevertheless, even if the pool of organs were to increase, it is not necessarily a panacea. Spain, though not strictly an opt-out system because it does not have an opt-out register (Etheredge 2021), is considered the gold-standard system for organ transplantation. But despite their success, Spain still has an insufficient number of organs, a growing kidney transplant wait list, and patients still die waiting for a transplant (Crespo et al. 2021). Kidney transplant wait lists continue to increase despite improving infrastructure, education, and the adoption of opt-out systems. Because only around 1% of people who die each year in the UK are eligible to donate their organs (NHS Blood and Transplant, 2022), it is becoming increasingly necessary to consider alternative approaches to increase the number of available organs for transplant."
Tuesday, August 30, 2022
Kidney news from Cambridge on possibility of removing blood type barriers
Here's some very preliminary kidney news (a press release) in The Guardian and at Cambridge, that could have the potential to have an impact sooner rather than later in helping potential transplant recipients with blood type O, who can only receive blood type O kidneys (which can be received by patients of any blood type)...
Researchers change blood type of kidney in transplant breakthrough University of Cambridge team’s work could significantly increase supply of organs for people with rarer blood types
"University of Cambridge researchers used a normothermic perfusion machine – a device that connects with a human kidney to pass oxygenated blood through the organ to better preserve it for future use – to flush blood infused with an enzyme through the deceased donor’s kidney.
"The enzyme removed the blood type markers that line the blood vessels of the kidney, which led to the organ being converted to type O."
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https://www.cam.ac.uk/stories/kidneybloodtype
The scientists mentioned are Professor Michael Nicholson and PhD student Serena MacMillan .
Thursday, August 25, 2022
Opt out organ donation in England and the Netherlands
Jansen, N. E., Williment, C., Haase-Kromwijk, B. J. J. M., & Gardiner, D. (2022). Changing to an Opt Out System for Organ Donation—Reflections From England and Netherlands. Transplant International, 133.
Abstract: Recently England and Netherlands have changed their consent system from Opt In to Opt Out. The reflections shared in this paper give insight and may be helpful for other nation considering likewise. Strong support in England for the change in legislation led to Opt Out being introduced without requiring a vote in parliament in 2019. In Netherlands the bill passed by the smallest possible majority in 2018. Both countries implemented a public campaign to raise awareness. In England registration on the Donor Register is voluntary. Registration was required in Netherlands for all residents 18 years and older. For those not already on the register, letters were sent by the Dutch Government to ask individuals to register. If people did not respond they would be legally registered as having “no objection.” After implementation of Opt Out in England 42.3% is registered Opt In, 3.6% Opt Out, and 54.1% has no registration. In contrast in Netherlands the whole population is registered with 45% Opt In, 31% Opt Out and 24% “No Objection.” It is too soon to draw conclusions about the impact on the consent rate and number of resulting organ donors. However, the first signs are positive."
...
"There had been many failed attempts to introduce Opt Out legislation to England over the last 30 years but was achieved on 20th May 2020. In October 2017 the Prime Minister stated her intention to shift “the balance of presumption in favour of organ donation” and “introduce an opt out system for donation.”
"Fortuitously a parliamentarian from the opposition party had successfully had his name drawn from a legislation ballot (a system which allows a few “Private Members Bills” to be considered by parliament from a randomly chosen subset of legislation suggestions), for a new Opt Out Bill. This led to an unusual alignment of opposing political parties, working together on a new policy. Due to this cross party support, the Bill progressed through Parliament and never had to be put to a vote.
"England’s Opt Out legislation built on the positive experience in Wales and Parliament was further reassured by the response to a public consultation on the draft Bill, which asked how Opt Out should be introduced. The Government usually expects between 200 and 500 responses; over 17,000 responses were received. The responses were supportive and gave a strong steer for the issues needing to be addressed.
"The main issues raised by the public were: the need for autonomy and individual choice; the role of the family; the need to respect faith and beliefs through the donation process. The government worked closely with NHSBT to identify ways to ensure that these issues were addressed. Ministerial commitments also secured additional resources such as increased recurrent funding.
"The final inspiration came from two young people—Max Johnson and Keira Ball. When the Bill was introduced, Max Johnson, a 9 year old boy, was in desperate need of a heart transplant. The UK media—particularly the Mirror newspaper—campaigned for the introduction of Opt Out legislation. Max’s life was saved through the gift of donation by Keira Ball, also aged nine, who tragically lost her life in a road traffic collision. The Opt Out legislation is known as Max and Keira’s Law, in their honour.
"Netherlands
"On the 1st of July 2020 the Opt Out system for organ donation was implemented in Netherlands. Changing the organ donation law from an Opt In consent system into an Opt Out system had not been easy. It took more than 12 years of political discussion to reach the milestone of a majority.
"In 2012 a member of the House of Representatives prepared a Bill to change the consent system into an “Active Donor Registration.” On the 16th of September 2016 the Bill was passed by the smallest possible majority in the House of Representatives, 75 members voted in favour of the Bill and 74 members against. On the 16th of February 2018 the vote in the Senate again ended in a close call, 38 senators voted in favour of the Bill and 36 members against. The Bill could only pass after a required amendment to develop a “Quality Standard Donation,” which describes the role of the doctor and the family in the donation conversation, based on the different outcomes of the Donor Register.
"The Active Donor Registration means that Dutch residents without a registration in the Donor Register, 7 million, will be asked by letter to register their donation preferences (same options as in the Opt In system). If they do not respond to a first and second letter, they will receive a third and final letter with the confirmation that they will be registered as having “No Objection” to organ and tissue donation. Under the new legislation “No Objection” would legally be considered the same as a registration of “Yes, I want to be an organ donor.” Registrations can be changed 24 h a day via the Internet. It could therefore be argued that while the change in law was to introduce Opt Out, it has similarities to a model of mandated choice for organ and tissue donation (6).
Wednesday, December 1, 2021
School choice using deferred acceptance algorithms increases competition for selective schools, by Terrier, Pathak and Ren
Here's a working paper from the LSE which concludes that making it safe for parents to truthfully report their preferences increases the competition for selective schools (called grammar schools, which prioritize students based on admission tests), with the unintended consequence of disadvantaging poorer families in England. The paper contains a good description of past and present school assignment regimes in England.
From immediate acceptance to deferred acceptance: effects on school admissions and achievement in England by Camille Terrier Parag A. Pathak and Kevin Ren, Centre for Economic Performance Discussion Paper No.1815, November 2021
"Abstract: Countries and cities around the world increasingly rely on centralized systems to assign students to schools. Two algorithms, deferred acceptance (DA) and immediate acceptance (IA), are widespread. The latter is often criticized for harming disadvantaged families who fail to get access to popular schools. This paper investigates the effect of the national ban of the IA mechanism in England in 2008. Before the ban, 49 English local authorities used DA and 16 used IA. All IA local authorities switched to DA afterwards, giving rise to a cross-market difference-in-differences research design. Our results show that the elimination of IA reduces measures of school quality for low-SES students more than high-SES students. After the ban, low-SES students attend schools with lower value-added and more disadvantaged and low-achieving peers. This effect is primarily driven by a decrease in low-SES admissions at selective schools. Our findings point to an unintended consequence of the IA to DA transition: by encouraging high-SES parents to report their preferences truthfully, DA increases competition for top schools, which crowds out low-SES students."
And here are the paper's concluding sentences:
" In England, selective schools pick students based on test scores, which favors high-SES parents. After the transition to DA, high-SES parents enroll at these schools at higher rates. Selective admissions are widespread throughout education, so our results provide an important caution to equity rationales for DA over IA in settings where selective schools have large market share."
Saturday, August 7, 2021
Real estate auctions for turtledoves: Klemperer, Baldwin and Teytelboym in the Economist
The Economist reports on efforts to reverse the decline of turtledove nesting sites:
How an auction is helping Britain’s turtle doves
"Paul Klemperer, Elizabeth Baldwin and Alex Teytelboym, all of Oxford University, are using economics to help. They have designed a reverse auction in which farmers bid publicly for contracts to provide suitable habitats. This is trickier than it sounds. Turtle doves need wildflower seeds to eat, shallow-sided open water to drink and thick scrubby hedgerows in which to nest—all in proximity. A farmer might wish to provide just one or two of these, and to rely on neighbours to provide the rest. Moreover, breeding pairs must be able to find the sites, but they must not be too clumped together. And finally, the habitats offered by farmers can vary in quality as well as price—a problem Mr Klemperer encountered during the global financial crisis, when designing an auction in which the Bank of England offered emergency loans to banks against collateral of varying quality.
"To solve it this time round, the economists constructed an index of turtle-dove happiness (tdh, or “ta-das”). An algorithm searches combinations of bids, seeking to maximise ta-das for a given budget. Bids both compete with and complement each other: a high-priced offer to grow wildflowers might beat a cheaper one if they would be nearer a nesting site, and would thus create more ta-das. The Royal Society for the Protection of Birds, a charity, has used the system in two pilot auctions in Norfolk and Suffolk, attracting 63 bidders. The latest closed in June, and seeds should be sown in the autumn.
"The experiments are funded by the government as part of a broader post-Brexit effort to redirect farming subsidies towards support for providing public goods. The European Union’s common agricultural policy, which rewards intensive farming, had led to the loss of diverse natural habitats for wildlife of all kinds."
Monday, June 28, 2021
Kidney exchange (including global kidney exchange), discussed at the European Society of Organ Transplantation meeting in Milan, Tuesday 29 June
ESOT: The 20th Congress of the European Society of Organ Transplantation, meeting (by Zoom) in Milan, Italy (so the talks start at 9am pacific time, noon Eastern time in U.S., tomorrow)
Models of kidney exchange and chains
Tuesday 29 June 18:00 (CEST)
18:00 – 18:12 Kidney exchange in UK Lisa Burnapp
18:12 – 18:24 Kidney exchange in EU: where we are? Peter Biro
18:24 – 18:36 Kidney exchange in US Michael Rees
18:36 – 18:48 Ethical and legal issue in kidney exchange Frederike Ambagtsheer
18:48– 19:00 Discussion Panellists
19:00 Conclusions Nizam Mamode
Registration is free via https://us02web.zoom.us/webinar/register/WN_3sfBEFxnQleNoYezQvyjbg.
Tuesday, September 15, 2020
Covid has slowed transplants in the UK
The Evening Standard has the story:
Organ transplant waiting list jumps to five-year high due to pandemic, new NHS figures show
by Naomi Ackerman
"The number people waiting for an organ transplant has soared to five-year high as a result of the coronavirus pandemic, new NHS figures have shown.
"NHS Blood and Transplant (NHSBT) said this week that an estimated 6,700 people are currently in need of a transplant across the UK - up from 6,138 prior to the start of the pandemic.
"The health body has estimated that the increase in patients waiting - expected to be the highest since 2015-16 - comes after services were impacted by the effects of the pandemic.
...
"It is hoped that the waiting list can be shortened going forward following the introduction of a new law in May, making organ donation "opt-out" rather than an active choice.
...
"The law will see that families are still consulted before organ donation goes ahead - the reason is why health officials have implored people to make their wishes about donation known to their families.
"NHSBT has said that thousands of "transplant opportunities" have been missed in recent years. In 2018-19, it reported that 835 families declined to support organ donation - with many families saying they did not know what their relative would have wanted."
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HT: Alex Chan
Sunday, December 3, 2017
Internet dating while Muslim
SingleMuslim.com: how the Yorkshire dating site transformed Muslim romance
It is one of the biggest dating sites in the world and after 17 years, it has has led to over 50,000 marriages.
"The UK site boasts nearly a million UK active users and the company is expanding internationally. (Traffic analysis suggests there are about 1.4m page views per month).Because it is in effect a marriage site rather than a dating site, it also claims a high rate of success. There have been 50,000 SingleMuslim.com weddings, and counting.
...
"When Younis originally set up his website, the problems came from fundamentalists. “Back in the day we used to have death threats,” he says. “All from anonymous keyboard warriors. They would be like ‘it is haram [forbidden] to display photographs of women’. People would have seen their sister on there.”
"Younis was unfazed. Now, he says, he doesn’t hear of anyone who is against what they are doing, mainly because, he believes, “everyone knows someone the site has helped”.
...
"You don’t have to spend very long on SingleMuslim.com to realise it is not Tinder. The options in creating a profile on the site require users to select their level of piety (Very religious/Somewhat religious/Prefer not to say) their sect (Shia/Sunni/Just Muslim) and appearance preferences (Hijab? Beard?).
“What we are not is this kind of swipe right, one-night stand kind of service,” Younis says. “People call it ‘halal dating’ and that’s fine. Halal means being wholesome and right in your faith.”
"About 10% of members join as a family. In those cases, traditionally the mums or the grannies use the site to do the matchmaking, Khan explains. What the company mostly promotes, though, is the opportunity to broaden that search as far as possible. The case studies on the site highlight couples who have crossed national and racial barriers to marry. “We are not SingleShia.com or SinglePakistanimuslim.com,” Younis suggests. There is an empowering impulse in this – and in the insistence that photographs must be full face. “Females who are fully covered don’t get in our galleries,” Khan says. “There is no point in having an image where you just see the eyes.”
Sunday, October 29, 2017
Family consent for deceased organ donation in Britain
"Organs from 505 registered donors could not be made available for transplant in the last five years because of objections from relatives.
...
"The law states that consent lies with the deceased, but in practice, relatives' wishes are always respected.
The NHS wants to reduce the number of "overrides" by encouraging prospective donors to talk to their relatives.
In England, NHS figures showed that 457 people died last year whilst waiting for an organ transplant."
Sunday, October 8, 2017
Uber's difficulties in London (and in general)
Understanding Uber: It’s Not About The App
Saturday, September 24, 2016
Tuesday, May 31, 2016
Gazumping in England: repugnant and soon to be illegal?
Relief for home buyers as the Government may ban 'gazumping'
"Gazumping could be banned by the Government, as it has emerged that officials have held private meetings with industry to discuss bringing forward the point at which house sales become legal, in line with Scotland.
"The radical move would prevent millions of British housing sales falling through as 18pc, or around 200,000 transactions collapse each year.
"A major reason is a plague of buyers outbidding others who have already put down an offer, a practice commonly known as "gazumping".
"It causes frustration and disappointment for buyers who think they have secured their dream home, only to find they lose it overnight to someone with more cash. It also routinely leaves frustrated would-be-buyers paying for bills for surveying and legal fees which can run into thousands of pounds, providing a further kick in the teeth.
...
"The meeting was used in part to discuss the idea of introducing to Britain the system which already exists in Scotland and in other countries in Europe, under which property sales are legally binding at the point where an offer is accepted by the buyer.
"At present deals made in Britain are only binding once the contracts have been exchanged, giving buyers with big deposits ample chance to "gazump".
While this Scottish-style system could make life much easier for buyers of British homes, experts predicted it would be very unpopular with sellers and could even put them off moving house. "
Sunday, December 27, 2015
There is no law against cannibalism in England
"Has José Salvador Alvarenga been reaching for the fava beans and chianti? The 36-year-old sailor survived at sea for more than a year after being cast adrift by a storm. But now the family of his fellow sailor, 22-year-old Ezequiel Córdoba, say the older man turned cannibal to survive. Alvarenga insists Córdoba died because he could not stomach the raw birds and turtle blood that were their only source of food. But Córdoba’s family are suing the Salvadorian fisherman for $1m for eating their relative.
Thursday, August 27, 2015
Assisted dying: the debate in England
‘There is nothing sacred about suffering’, insist faith leaders in assisted dying call--Bishops, priests and leading Rabbis break ranks with mainstream religious case opposition to assisted dying
"Religious teachings that elevate suffering and pain as something “sacred” should not be used to prevent terminally ill people taking their own lives, leading Christian and Jewish clerics have insisted.
"An alliance of bishops, priests and rabbis have broken ranks with the religious establishment to voice support for plans to change the law to allow a form of assisted suicide in the UK for the first time.
"In a letter to The Daily Telegraph, they argue that far from being a sin, helping terminally ill people to commit suicide should be viewed simply as enabling them to “gracefully hand back” their lives to God.
"There is, they insist “nothing sacred” about suffering in itself and no one should be “obliged to endure it”, they insist.
"Signatories of the letter, in support of a bill to be debated by MPs next month, include Lord Carey, the former Archbishop of Canterbury, who stunned the Church of England last year when he announced that he had changed his mind on the issue.
...
"MPs are due to debate an Assisted Dying Bill tabled by the Labour backbencher Rob Marris next month.
While most of the major religious groups in the UK have voiced opposition, some polls suggest a majority of people who identify themselves with a faith are in favour of relaxing the law."
Tuesday, December 30, 2014
Early admissions come to English universities
Top universities 'ignoring final A-level grades' in race to sign up students
"Universities such as Lancaster and Birmingham are making record numbers of "unconditional offers" – places awarded irrespective of final A-level grades – in 2015"
"Leading universities have been accused of undermining A-levels by accepting students before they sit their final exams in a “desperate” rush to fill places.
"Research by the Telegraph shows universities are preparing to make increasing numbers of “unconditional offers” to sixth-formers next year.
"Top research institutions including Birmingham, Lancaster, Nottingham, Leicester, Sussex and Queen Mary, University of London, will admit students en masse in some subjects without waiting for results in August.
"Numbers are expected to significantly exceed the 12,000 unconditional offers made across the UK this year, with one university alone saying it will make 10,000 in 2015.
The move coincides with a government decision to abolish all restrictions on student recruitment in England for the first time in 2015 – creating a free market in undergraduate admissions.
"It has led to intense competition between universities to sign up the most talented sixth-formers before they are attracted to opposing institutions.
"In most cases, admissions tutors will make places available to candidates based on past performance in GCSEs and their predicted A-level grades, meaning students will win places even if they go on to fail their summer exams."
Tuesday, August 26, 2014
Non-directed kidney donation up in Britain
"Altruistic kidney donation has, in the past year, increased by 55 per cent, with 118 living people donating a kidney. The practice only became legal in 2006, and the following year only six procedures were recorded. Since then the numbers have risen exponentially.
Transplant experts believe that cases such as that of the 85-year-old woman who this year became Britain’s oldest living kidney donor – “Why do I need two kidneys to sit at home knitting and watching television?”, she asked – have inspired others to follow suit.
Before 2006, only family and close friends were allowed to give up their kidney for people suffering from kidney dysfunction. The authorities were wary of a trade in organs that could lead to an exploitative or coercive relationship between recipient and donor.
The current legislation, drawn to prevent this, states that donors are not allowed to know the identity of the recipient, although recipients are allowed to get in touch with donors, if they choose to, after the operation. This is so that the recipient is not made to feel any moral or financial obligation.
Monday, February 11, 2013
Real estate ads in Britain: "no upward chain"
It turns out that right now in England, a not-so-rare feature of ads to sell houses is the phrase "No upward chain." What it means, apparently, is that this house is available to be bought/sold right now, without the owner having to wait to buy a new house before closing on the deal.
HT: Brit Grosskopf