Kidney Exchange among Austria, Czech Republic, and Israel

 Here's an article that includes description of the joint Austria, Czech Republic and Israel kidney exchanges.

Böhmig, Georg A., Thomas Müller‐Sacherer, and Ondrej Viklicky. "Kidney Paired Donation—European Transnational Experience in Adults and Opportunities for Pediatric Kidney Transplantation." Pediatric Transplantation 28, no. 6 (2024): e14840.

"One approach to expanding the pool, akin to deceased donor kidney transplantation through the transnational Eurotransplant Organization, involves the establishment of cross-border KPD joint programs. In Europe, several joint programs have successfully conducted such transplants, one of which is the Scandiatransplant Exchange Program, inaugurated in 2019. As of February 2023, this program has facilitated 49 transplantations [29]. Another transnational initiative, the focus of this article, is the joint program involving Austria, the Czech Republic, and Israel. This collaboration resulted in the first transnational live donor kidney exchange in Europe, a two-way exchange between Vienna and Prague in 2017 [30].

"The Vienna and Prague Kidney Paired Donation (KPD) programs were merged in 2015 following a consensus on medical, psychological, and immunological requirements [23]. ... Both programs agreed on a binational algorithm, utilizing a computer algorithm developed in Prague. This algorithm not only facilitates the calculation of ABO-incompatible combinations but also includes the option of Non-Directed Altruistic Donor (NEAD) chains initiated by altruistic donors [23].

...

"Recent developments in the transnational program include its expansion to additional centers. Prague initiated a transnational cooperation with the national KPD program in Israel, successfully conducting the first ring exchange in 2019. In this context, transplantations cannot be realized simultaneously due to the financial burden associated with the need for two private flights. Later, this cooperation extended to the Vienna center, leading to the first exchange between Vienna and Israel in 2022, involving a simultaneous three-way chain with one Vienna and two Israel pairs. Innsbruck has also joined the international KPD program as a second Austrian center, participating in local exchanges and one 2-way exchange with Prague (2020). A good example of different approaches in timing of surgeries among Prague and Israel centers (non-simultaneous) in one hand and Vienna (simultaneous surgeries) in the other hand is Czech-Austrian-Israel international NEAD chain initiated in Prague which has lasted for several years, prioritized smaller exchanges and has not been terminated so far. Such a NEAD chain used both altruistic and bridge donors in Prague. Terminated NEAD chain may allow to prioritize patient at special need. For example, our short 3-country NEAD chain was terminated to offer transplantation to a previous kidney donor who donated 20 years ago but unfortunately developed end stage kidney disease. Such approach may have implications also in pediatrics."

Kidney exchange between Israel and the Czech Republic

 The Jerusalem Post reports another kidney exchange between Israel and the Czech Republic:

Miraculous kidney donation between friends spans continents and save lives. The complex and sensitive cross-continental operation required coordination between senior officials in both countries.   https://www.jpost.com/international/article-804396   By JERUSALEM POST STAFF  MAY 30, 2024 18:39

"it was soon discovered that Glaor was not a direct match for a transplant, and their medical details were entered into the National Transplant Center's cross-matching database. The entry resulted in an international kidney transplant exchange in which Glaor donated his kidney to a patient in the Czech Republic, and the wife of the Czech patient donated her kidney to Shitrit.

"The complex and sensitive cross-continental operation required coordination between senior officials in both countries, with an emphasis on the precise timing of operating rooms, flights, and quick security and customs arrangements.

"The operation began in the middle of the night at the Hadassah University Medical Center in Jerusalem’s Ein Kerem. It was managed and coordinated by the National Transplant Center.

"Dr. Tamar Ashkenazi, director of the National Transplant Center, was in charge of coordinating the transplant.  Alongside her on the flight to Prague were coolers containing two kidneys that were removed overnight from two Israeli donors at Hadassah Ein Kerem, which were intended for transplantation in two Czech patients. 

"In the evening, at around 10 p.m., the transplants in Israel were completed, and the Czech kidneys successfully functioned in the bodies of the Israeli recipients, as reported similarly from Prague regarding the Israeli kidneys that were transplanted in the Czech Republic.

""We planned the process precisely, and were in constant contact with our counterparts in the Czech Republic regarding the surgical issues. Every action that takes place is critical and impacts the continuation of the operation," said Dr. Ashraf Imam, a senior surgeon in the transplant unit at Hadassah, who participated in the transplant operation."

Celebrating the 30th Anniversary of CERGE-EI: Supporting Excellence in Economic Research and Education in Post-Communist Societies

In 1990, when I was on the faculty of the University of Pittsburgh (where I happily taught from 1982-1998), my colleague Jan Svenjar was instrumental in founding  a graduate program in Economics at Charles University, which soon after became  CERGE-EI, which is now about to celebrate it's 30th anniversary.  It is an appropriate time once again to be thinking about post-communist Europe.

Celebrating the 30th Anniversary of CERGE-EI: Supporting Excellence in Economic Research and Education in Post-Communist Societies

Tuesday, April 26, 2022 ● 4:00 p.m. Bohemian National Hall, 321 East 73rd Street, New York City

CERGE-EI has reached a pivotal moment of change in its history. The 30th Anniversary Celebration of CERGE-EI, hosted by the CERGE-EI U.S. Foundation in conjunction with the Consulate General of the Czech Republic in New York, will be both a reflection of CERGE-EI’s impact over the last thirty years and an opportunity to lay out our vision for the future.

The war in Ukraine and its impact on the surrounding region have established that the Cold War whose ending we celebrated more than 30 years ago has revived and is heating up. Now more than ever, initiatives to raise the standards of economics education and leadership have a critical role to play in supporting national and regional stability.

For the 30th Anniversary, we are honored to be supported by a Host Committee of Nobel Memorial Prize in Economic Sciences Laureates.

Professor
Francis Fukuyama

Professor
Deirdre McCloskey

Professor
Sir Angus Deaton

Professor
Paul Krugman

Professor
Branko Milanović

Professor
Jeffrey Sachs

Professor
Jan Švejnar

International kidney exchange between Israel and Czech Republic

The news embargo is over for last week's kidney exchange chain between Israel and the Czech Republic. (On the Israeli side, the necessary software was supplied by Itai Ashlagi, here at Stanford.)

Itai writes:
"Some background: in August 2019 there was an agreement between Israel and Czech republic to check the possibility of kidney exchanges. This was initiated by Prof. Eitan Mor from Israel  and Dr. Proniak from the Czech Republic and the whole operation was conducted by the national Israeli center for transplantation led by Dr. Tamar Askenazi and their counterpart in Czech republic."

The Israeli database contains a list of all pairs, and uses kidney exchange software donated to Israel by Itai Ashlagi and Sukolsak Sakshuwong.   Czech software was used in Prague to identify the chain.

Here's the story from News1 in Israel:

6 transplants thanks to the exchange of kidney donations between Israel and the Czech Republic

"At 5 a.m., two kidneys from two donors were removed from Beilinson Hospital. One kidney was packed in ice cooler and transported by ambulance to Ben Gurion Airport.

"About an hour after taking off from Israel, an operation to remove a Czech donor kidney was started at the Prague Hospital. At the same time, Bilinson's second kidney was transplanted, and surgery was performed to remove a kidney at Hadassah Hospital – which was transported by ambulance to Bilinson's transplant.

"At 12:30 the kidney cooler from Israel landed at the Prague airport. A vehicle was waiting by the plane and moved to the mirroring spot. At this point, Dr. Jiri Froniac, director of the Prague Transplant Program and Dr. Ashkenazi from Israel, met and exchanged documents while the coolers were [scanned].

"At the same time, the kidney from Hadassah Hospital was transferred to Beilinson for a transplant. An hour later, the Israeli plane took off from Prague back to Israel with a cooler containing the kidney from the Czech donor. The kidney came to the operating room in Hadassah and before the evening was transplanted in a patient.
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Diagram of the exchange between IKEM in the Czech Republic and Hadassah and Beilinson Hospitals in Israel

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Here's the story in the Jerusalem Post (I don't have a link yet, this is a picture):

And see this related older story about Itai Ashlagi's software:

New software to help increase kidney matches for transplants

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And here is the story in the Czech news, forwarded by Pavel Chromy.

Čeští lékaři poprvé provedli párovou výměnu ledvin s Izraelem
[Google translate: Czech doctors first performed paired kidney replacement with Israel]
"In the first half of December, doctors from the Prague Institute of Clinical and Experimental Medicine (IKEM) and two Israeli hospitals performed their first paired kidney exchange between the two countries. Three beneficiaries from the Czech Republic and three from Israel received the new authority. This is the first time a pair exchange has taken place with a non-European country, said IKEM director Michal Stiborek at a press conference."