John Gurdon (1933-2025)

One hope for a future free of the need for human organ transplants is that it might become possible to re-initiate the process by which embryos originally grow their own kidneys from stem cells, i.e. from cells that are "pluripotent,"  in that they retain the possibility  of growing into any of the organs with which we humans come originally equipped.

Great progress is being made in that direction, although  obviating the need for transplants is still only a distant hope.   I had the good fortune to meet two of the pioneers of those efforts, in Stockholm in 2012, when that year's Nobel Prize in Physiology or Medicine was awarded jointly to Sir John B. Gurdon and Shinya Yamanaka "for the discovery that mature cells can be reprogrammed to become pluripotent"  

John has now died, at the age of 92.  I hope he  derived great satisfaction from the fact that his pioneering work is continuing to lead to steady progress.

 Here's his obituary from the Guardian, which contains an anecdote that I recall he shared in Stockholm. His story should give comfort to students unappreciated by teachers who don't realize that students retain a good deal of pluripotency regarding what kind of adults and scholars they will become.

 Sir John Gurdon obituary. Biologist who won the Nobel prize for discovering that adult cells can be reprogrammed.  byGeorgina Ferry

 " His career narrowly missed being driven off course by a report from his biology teacher, placing him last in his year and dismissing his idea of becoming a scientist as a “sheer waste of time, both on his part, and of those who have to teach him.”